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Bcl-2 Protein (AA 1-210) (His tag)

BCL2 宿主: 人 Recombinant > 95.0 % as determined by SDS-PAGE.
产品编号 ABIN620234
发货至: 中国
  • 抗原 See all Bcl-2 (BCL2) 蛋白
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
    蛋白类型
    Recombinant
    产品特性
    AA 1-210
    宿主
    • 11
    • 4
    • 2
    • 2
    • 2
    宿主
    请咨询
    标记
    This Bcl-2 protein is labelled with His tag.
    产品特性
    Recombinant Human B-Cell Leukemia/Lymphoma 2, His6-tagged
    纯度
    > 95.0 % as determined by SDS-PAGE.
    Top Product
    Discover our top product BCL2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    The protein contains 10mM Tris-HCL pH-8, 1mM EDTA and 250mM NaCl.Suspend BclXL in 100ul of 0.5M Acetic acid, over night at 4°C. Dilute 10 fold into selected buffer system. Bcl-XL has tendency to form intramolecular disulfide bond, 5mM DTT is recommended in assay buffer. When running SDS-PAGE gel, 10mM DTT is recommended.
    储存条件
    -20 °C
  • 抗原
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
    别名
    B-Cell Leukemia/Lymphoma 2 (BCL2 产品)
    别名
    Bcl-2 Protein, PPP1R50 Protein, bcl-2 Protein, AW986256 Protein, C430015F12Rik Protein, D630044D05Rik Protein, D830018M01Rik Protein, BCL-2 Protein, Bcl2 Protein, BCL2, apoptosis regulator Protein, B cell leukemia/lymphoma 2 Protein, B-cell CLL/lymphoma 2a Protein, B-cell CLL/lymphoma 2 protein Protein, BCL2 Protein, Bcl2 Protein, bcl2a Protein, BCL-2 Protein
    背景
    Bcl-XL Human Recombinant produced in E. coli is a single, non-glycosylated polypeptide chain containing AA 1-210. The Bcl-XL is expressed as His-Tag fusion protein and purified by proprietary chromatographic techniques. Introduction: Bcl-XL is a transmembrane protein located in the mitochondrial membranes of cells that are long-lived and postmitotic, such as adult brain cells. It plays arole in the signal transduction pathway of the FAS-Ligand. Bcl-XL is an anti-apoptotic protein which is a member of the Bcl-2 family which are able to form heterodimers, and this is an significant event in the regulation of apoptosis. BCL-XL is involved in the survival of cancer cells. Bcl-xL is the leading monitor of apoptosis/active cell suicide. Bcl-xL has cell death repressor activity and therefore acts as a survival protein. Synonyms: BclXL, Bcl-X(L), Bcl-XL.
    途径
    MAPK Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
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