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ICOSLG Protein (AA 19-256) (hIgG-His-tag)
ICOSLG
宿主: 人
宿主: Baculovirus infected Insect Cells
Recombinant
> 90 % by SDS - PAGE
SDS
产品细节
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抗原
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ICOSLG
(Inducible T-Cell Co-Stimulator Ligand (ICOSLG))
蛋白类型
Recombinant
产品特性
AA 19-256
宿主
All origins for ICOSLG 蛋白
人
资源
All sources for ICOSLG 蛋白
Baculovirus infected Insect Cells
标记
This ICOSLG protein is labelled with hIgG-His-tag.
应用范围
SDS-PAGE (SDS)
序列
ADPDTQEKEV RAMVGSDVEL SCACPEGSRF DLNDVYVYWQ TSESKTVVTY HIPQNSSLEN VDSRYRNRAL MSPAGMLRGD FSLRLFNVTP QDEQKFHCLV LSQSLGFQEV LSVEVTLHVA ANFSVPVVSA PHSPSQDELT FTCTSINGYP RPNVYWINKT DNSLLDQALQ NDTVFLNMRG LYDVVSVLRI ARTPSVNIGC CIENVLLQQN LTVGSQTGND IGERDKITEN PVSTGEKNAA TLEPKSCDKT HTCPPCPAPE LLGGPSVFLF PPKPKDTLMI SRTPEVTCVV VDVSHEDPEV KFNWYVDGVE VHNAKTKPRE EQYNSTYRVV SVLTVLHQDW LNGKEYKCKV SNKALPAPIE KTISKAKGQP REPQVYTLPP SRDELTKNQV SLTCLVKGFY PSDIAVEWES NGQPENNYKT TPPVLDSDGS FFLYSKLTVD KSRWQQGNVF SCSVMHEALH NHYTQKSLSL SPGKHHHHHH
纯度
> 90 % by SDS - PAGE
内毒素水平
< 1.0 EU per 1 microgram of protein (determined by LAL method)
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
1 mg/mL
缓冲液
Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
储存条件
4 °C,-20 °C,-80 °C
储存方法
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
目标详细情况
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抗原
ICOSLG
(Inducible T-Cell Co-Stimulator Ligand (ICOSLG))
别名
ICOSLG (ICOSLG 产品 )
别名
ICOSLG Protein, AU044799 Protein, B7-H2 Protein, B7RP-1 Protein, B7h Protein, BG071784 Protein, GI50 Protein, GL50 Protein, GL50-B Protein, ICOS-L Protein, Icoslg Protein, LICOS Protein, Ly115l Protein, mKIAA0653 Protein, B7H2 Protein, B7RP1 Protein, CD275 Protein, ICOSL Protein, Icosl Protein, RGD1562791 Protein, inducible T-cell costimulator ligand Protein, icos ligand Protein, inducible T-cell co-stimulator ligand Protein, ICOSLG Protein, Icosl Protein, Icoslg Protein
背景
ICOSLG, also known as ICOS ligand isoform a, is a number of the B7 family of co-stimulatory molecules related to B7-1 and B7-2. This protein is a transmembrane glycoprotein with extracellular IgV and IgC domains, and binds to ICOS on activated T cells. Its dependent signaling may play an active role in a proliferative response rather than in cytokine and chemokine production. Recombinant human ICOSLG, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
分子量
53.7kDa (480aa) 50-70kDa (SDS-PAGE under reducing conditions.)
NCBI登录号
NP_056074
UniProt
O75144
途径
Production of Molecular Mediator of Immune Response , Activated T Cell Proliferation
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ICOSLG 蛋白
ICOSLG Protein (AA 19-256) (hIgG-His-tag) (ABIN5854908)