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SIRPA Protein (AA 32-373) (His tag)

SIRPA 宿主: 大鼠 宿主: Baculovirus infected Insect Cells Recombinant > 95 % by SDS - PAGE SDS
产品编号 ABIN5854453
发货至: 中国
  • 抗原 See all SIRPA 蛋白
    SIRPA (Signal-Regulatory Protein alpha (SIRPA))
    蛋白类型
    Recombinant
    产品特性
    AA 32-373
    宿主
    • 30
    • 19
    • 5
    • 4
    • 1
    大鼠
    资源
    • 35
    • 7
    • 7
    • 6
    • 2
    • 2
    Baculovirus infected Insect Cells
    标记
    This SIRPA protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    KELKVTQADK SVSVAAGDSA TLNCTVSSLT PVGPIKWFKG EGQNRSPIYS FIGGEHFPRI TNVSDATKRN NMDFSICISN VTPEDAGTYY CVKFQKGIVE PDTEIKSGGG TTLYVLAKPS SPEVSGPDSR GSPGQTVNFT CKSYGFSPRN ITLKWLKNGK ELSHLETTIS SKSNVSYNIS STVSVKLSPE DIHSRVICEV AHVTLEGRPL NGTANFSNII RVSPTLKITQ QPLTPASQVN LTCQVQKFYP KALQLNWLEN GNLSRTDKPE HFTDNRDGTY NYTSLFLVNS SAHREDVVFT CQVEHDSQPA ITENHTVRAF AHSSSGGSME TIPDNNAYYN WNVEHHHHHH
    纯度
    > 95 % by SDS - PAGE
    内毒素水平
    < 1.0 EU per 1 microgram of protein (determined by LAL method)
    Top Product
    Discover our top product SIRPA 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • 抗原
    SIRPA (Signal-Regulatory Protein alpha (SIRPA))
    别名
    Tyrosine-protein phosphatase non-receptor type substrate 1 (SIRPA 产品)
    别名
    BIT Protein, CD172A Protein, MFR Protein, MYD-1 Protein, P84 Protein, PTPNS1 Protein, SHPS1 Protein, SIRP Protein, SIRPA Protein, SIRP-A1 Protein, SIRP-B1 Protein, AI835480 Protein, Bit Protein, CD172a Protein, Ptpns1 Protein, SHP-1 Protein, SHPS-1 Protein, swc3 Protein, signal regulatory protein alpha Protein, myeloperoxidase Protein, signal-regulatory protein alpha Protein, tyrosine-protein phosphatase non-receptor type substrate 1 Protein, SIRPA Protein, MPO Protein, LOC458039 Protein, LOC100400378 Protein, LOC100590224 Protein, Sirpa Protein
    背景
    SIRPA, also known as tyrosine-protein phosphatase non-receptor type substrate 1, is an immunoglobulin-like cell surface receptor for CD47. It supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. It may play a key role in intracellular signaling during synaptogenesis and in synaptic function. It is involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. Recombinant rat SIRPA, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
    分子量
    38.5kDa (350aa) 57-70kDa (SDS-PAGE under reducing conditions)
    NCBI登录号
    NP_037148
    UniProt
    P97710
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