Ephrin A5 Protein (EFNA5) (AA 21-203) (His tag)
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- 抗原 See all Ephrin A5 (EFNA5) 蛋白
- Ephrin A5 (EFNA5)
- 蛋白类型
- Recombinant
- 产品特性
- AA 21-203
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宿主
- 大鼠
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资源
- 酵母菌
- 标记
- This Ephrin A5 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- QDPGSKVVAD RYAVYWNSSN PRFQRGDYHI DVCINDYLDV FCPHYEDSVP EDKTERYVLY MVNFDGYSAC DHTSKGFKRW ECNRPHSPNG PLKFSEKFQL FTPFSLGFEF RPGREYFYIS SAIPDNGRRS CLKLKVFVRP TNSCMKTIGV RDRVFDVNDK VENSLEPADD TVHESAEPSR GEN
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product EFNA5 蛋白
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Ephrin A5 (EFNA5) (Active) protein (His tag)
EFNA5 宿主: 小鼠 宿主: 人细胞 Recombinant > 90 % as determined by SDS-PAGE Active
Ephrin A5 (EFNA5) (AA 114-203) protein (GST tag)EFNA5 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Ephrin A5 (EFNA5) (AA 21-203), (full length) protein (His tag)EFNA5 宿主: 大鼠 宿主: 酵母菌 Recombinant > 90 % ELISA
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- Ephrin A5 (EFNA5)
- 别名
- EFNA5 (EFNA5 产品)
- 别名
- EFNA5 Protein, af1 Protein, efl5 Protein, rags Protein, eplg7 Protein, lerk7 Protein, AL-1 Protein, AV158822 Protein, EFL-5 Protein, Ephrin-A5 Protein, Epl7 Protein, LERK-7 Protein, RAGS Protein, Lerk7 Protein, AF1 Protein, EFL5 Protein, EPLG7 Protein, GLC1M Protein, LERK7 Protein, ephrin A5 Protein, EFNA5 Protein, efna5 Protein, Efna5 Protein
- 背景
- Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Induces compartmentalized signaling within a caveolae-like mbrane microdomain when bound to the extracellular domain of its cognate receptor. This signaling event requires the activity of the Fyn tyrosine kinase. Activates the EPHA3 receptor to regulate cell-cell adhesion and cytoskeletal organization. With the receptor EPHA2 may regulate lens fiber cells shape and interactions and be important for lens transparency maintenance. May function actively to stimulate axon fasciculation. The interaction of EFNA5 with EPHA5 also mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion. Cognate/functional ligand for EPHA7, their interaction regulates brain development modulating cell-cell adhesion and repulsion .
- 分子量
- 23.2 kDa
- UniProt
- P97605
- 途径
- RTK signaling
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