Ephrin A5 Protein (EFNA5) (AA 21-203) (Fc Tag)
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Quick Overview for Ephrin A5 Protein (EFNA5) (AA 21-203) (Fc Tag) (ABIN7318439)
抗原
See all Ephrin A5 (EFNA5) 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 21-203
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标记
- This Ephrin A5 protein is labelled with Fc Tag.
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原理
- Recombinant Human Ephrin-A5/EFNA5 Protein (Fc Tag)
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序列
- Gln21-Asn203
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产品特性
- Recombinant Human Ephrin-A5 is produced by our Mammalian expression system and the target gene encoding Gln21-Asn203 is expressed with a Fc tag at the C-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- Ephrin A5 (EFNA5)
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别名
- Ephrin-A5/EFNA5
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背景
- AL-1,EFNA5,EPH-related receptor tyrosine kinase ligand 7,EPLG7,Ephrin-A5,LERK-7,LERK7,Ephrin-A5 (EFNA5) belongs to the ephrin family,contains 1 ephrin RBD (ephrin receptor-binding) domain. Ephrin-A5 is a cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. It binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The interaction of EFNA5 with EPHA5 also mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion. Cognate/functional ligand for EPHA7, their interaction regulates brain development modulating cell-cell adhesion and repulsion.
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分子量
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Calculated MW: 48.3 kDa
Observed MW: 55-60 kDa
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基因ID
- 1946
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UniProt
- P52803
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途径
- RTK signaling
抗原
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