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Ephrin A5 Protein (EFNA5) (AA 21-203) (Fc Tag)

This Recombinant Ephrin A5 protein is expressed in HEK-293 Cells.
产品编号 ABIN7318439
发货至: 中国
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Quick Overview for Ephrin A5 Protein (EFNA5) (AA 21-203) (Fc Tag) (ABIN7318439)

抗原

See all Ephrin A5 (EFNA5) 蛋白
Ephrin A5 (EFNA5)

蛋白类型

Recombinant

宿主

  • 10
  • 3
  • 2
  • 1

资源

  • 4
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  • 2
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  • 1
HEK-293 Cells

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 产品特性

    AA 21-203

    标记

    This Ephrin A5 protein is labelled with Fc Tag.

    原理

    Recombinant Human Ephrin-A5/EFNA5 Protein (Fc Tag)

    序列

    Gln21-Asn203

    产品特性

    Recombinant Human Ephrin-A5 is produced by our Mammalian expression system and the target gene encoding Gln21-Asn203 is expressed with a Fc tag at the C-terminus.

    过滤

    0.2 μm filtered

    内毒素水平

    < 1.0 EU per μg of the protein as determined by the LAL method.

    Biological Activity Comment

    Not validated for activity
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    Ephrin A5 (EFNA5)

    别名

    Ephrin-A5/EFNA5

    背景

    AL-1,EFNA5,EPH-related receptor tyrosine kinase ligand 7,EPLG7,Ephrin-A5,LERK-7,LERK7,Ephrin-A5 (EFNA5) belongs to the ephrin family,contains 1 ephrin RBD (ephrin receptor-binding) domain. Ephrin-A5 is a cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. It binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The interaction of EFNA5 with EPHA5 also mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion. Cognate/functional ligand for EPHA7, their interaction regulates brain development modulating cell-cell adhesion and repulsion.

    分子量

    Calculated MW: 48.3 kDa

    Observed MW: 55-60 kDa

    基因ID

    1946

    UniProt

    P52803

    途径

    RTK signaling
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