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Ephrin A5 Protein (EFNA5) (His tag)

EFNA5 宿主: 小鼠 宿主: 人细胞 Recombinant > 90 % as determined by SDS-PAGE Active
产品编号 ABIN7320515
发货至: 中国
  • 抗原 See all Ephrin A5 (EFNA5) 蛋白
    Ephrin A5 (EFNA5)
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 7
    • 2
    • 2
    • 1
    小鼠
    资源
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    人细胞
    标记
    This Ephrin A5 protein is labelled with His tag.
    原理
    Recombinant Mouse Ephrin-A5/EFNA5 Protein (His Tag)(Active)
    序列
    Gln21-Gln206
    产品特性
    Recombinant Mouse Ephrin-A5 is produced by our Mammalian expression system and the target gene encoding Gln21-Gln206 is expressed with a 6His tag at the C-terminus.
    纯度
    > 90 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Biological Activity Comment
    Immobilized Human EphA8-Fc(Cat: PKSH032386) at 1.5μg/ml(100 μl/well) can bind Human EFNA5-His. The ED50 of EFNA5-His is 12.63ug/ml .
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    Ephrin A5 (EFNA5)
    别名
    Ephrin-A5/EFNA5 (EFNA5 产品)
    别名
    EFNA5 Protein, af1 Protein, efl5 Protein, rags Protein, eplg7 Protein, lerk7 Protein, AL-1 Protein, AV158822 Protein, EFL-5 Protein, Ephrin-A5 Protein, Epl7 Protein, LERK-7 Protein, RAGS Protein, Lerk7 Protein, AF1 Protein, EFL5 Protein, EPLG7 Protein, GLC1M Protein, LERK7 Protein, ephrin A5 Protein, EFNA5 Protein, efna5 Protein, Efna5 Protein
    背景

    Background: Ephrin-A5 is a glycosylphosphatidylinositol (GPI)-anchored protein of the ephrin-A subclass of ephrin ligands that binds to the EphA subclass of Eph receptors. Ephrin-A5 has also been shown to bind to the EphB2 receptor. It is crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Ephrin-A5 binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.

    Synonym: Ephrin-A5, AL-1, EPH-related receptor tyrosine kinase ligand 7, Epl7, Eplg7, Lerk7, Efna5,

    分子量
    22.5 kDa
    UniProt
    O08543
    途径
    RTK signaling
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