FUS Protein (AA 136-608) (His-SUMO Tag)
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- 抗原 See all FUS 蛋白
- FUS (Fused in Sarcoma (FUS))
- 蛋白类型
- Recombinant
- 产品特性
- AA 136-608
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宿主
- Canine Distemper Virus (CDV)
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资源
- 大肠杆菌（E. Coli）
- 标记
- This FUS protein is labelled with His-SUMO Tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- QIHWDNLSTI GIIGTDNVHY KIMTRPSHQY LVIKLIPNAS LIENCTKAEL GEYEKLLNSV LEPINQALTL MTKNVKPLQS LGSGRRQRRF AGVVLAGVAL GVATAAQITA GIALHQSNLN AQAIQSLRTS LEQSNKAIEE IREATQETVI AVQGVQDYVN NELVPAMQHM SCELVGQRLG LRLLRYYTEL LSIFGPSLRD PISAEISIQA LIYALGGEIH KILEKLGYSG SDMIAILESR GIKTKITHVD LPGKFIILSI SYPTLSEVKG VIVHRLEAVS YNIGSQEWYT TVPRYIATNG YLISNFDESS CVFVSESAIC SQNSLYPMSP LLQQCIRGDT SSCARTLVSG TMGNKFILSK GNIVANCASI LCKCYSTSTI INQSPDKLLT FIASDTCPLV EIDGATIQVG GRQYPDMVYE GKVALGPAIS LDRLDVGTNL GNALKKLDDA KVLIDSSNQI LETVRRSSFN FGS
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product FUS 蛋白
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Fused in Sarcoma (FUS) (AA 287-376) protein (His-IF2DI Tag)
FUS 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
Fused in Sarcoma (FUS) (AA 1-526) protein (Strep Tag)Crystallography grade FUS 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Fused in Sarcoma (FUS) (AA 1-518) protein (Strep Tag)Crystallography grade FUS 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Fused in Sarcoma (FUS) protein (Myc-DYKDDDDK Tag)FUS 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Fused in Sarcoma (FUS) (AA 137-574) protein (His tag)FUS 宿主: Human respiratory syncytial virus B 宿主: 酵母菌 Recombinant > 90 % SDS
Fused in Sarcoma (FUS) (AA 27-529) protein (His tag)FUS 宿主: Human respiratory syncytial virus A 宿主: 酵母菌 Recombinant > 90 % SDS
Fused in Sarcoma (FUS) (AA 1-198), (partial) protein (GST tag)FUS 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 95 % ELISA
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- FUS (Fused in Sarcoma (FUS))
- 别名
- FUS (FUS 产品)
- 别名
- ALS6 Protein, ETM4 Protein, FUS1 Protein, HNRNPP2 Protein, POMP75 Protein, TLS Protein, D430004D17Rik Protein, D930039C12Rik Protein, Fus1 Protein, Tls Protein, FUS/TLS Protein, FUS RNA binding protein Protein, fused in sarcoma Protein, FUS Protein, Fus Protein
- 物质类
- Viral Protein
- 背景
- Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell mbrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell mbranes. Directs fusion of viral and cellular mbranes leading to delivery of the nucleocapsid into the cytoplasm. This fusion is pH independent and occurs directly at the outer cell mbrane. The trimer of F1-F2 (F protein) probably interacts with H at the virion surface. Upon HN binding to its cellular receptor, the hydrophobic fusion peptide is unmasked and interacts with the cellular mbrane, inducing the fusion between cell and virion mbranes. Later in infection, F proteins expressed at the plasma mbrane of infected cells could mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis .
- 分子量
- 67.5 kDa
- UniProt
- P12569
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