FUS 蛋白
(Fused in Sarcoma (FUS))
This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| FUS Protein (AA 287-376) (His-IF2DI Tag) | 人 | 大肠杆菌（E. Coli） |
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| FUS Protein (His-SUMO Tag) | 人 | 大肠杆菌（E. Coli） |
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| FUS Protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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| FUS Protein (Myc-DYKDDDDK Tag) | 人 | HEK-293 Cells |
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| FUS Protein (AA 1-198, partial) (GST tag) | 人 | 大肠杆菌（E. Coli） |
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| FUS Protein (AA 27-529) (His tag) | Human respiratory syncytial virus A | 酵母菌 |
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| FUS Protein (AA 137-574) (His tag) | Human respiratory syncytial virus B | 酵母菌 |
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| FUS Protein (AA 136-608) (His-SUMO Tag) | Canine Distemper Virus (CDV) | 大肠杆菌（E. Coli） |
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| FUS Protein (AA 193-444) (His tag) | 人 | Bacteria |
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| FUS Protein (AA 282-367) (His-SUMO Tag) | 人 | Bacteria |
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| FUS Protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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| FUS Protein (His-SUMO Tag) | 人 | 大肠杆菌（E. Coli） |
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Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- SDS (SDS-PAGE: 所列应用)
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Protein
- SDS (SDS-PAGE: 所列应用)
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Protein
- WB (Western Blotting: 有验证图片)
- AbP (Antibody Production: 所列应用)
- STD (Standard: 所列应用)
5 references - 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- 95 %
Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- Human respiratory syncytial virus A
- 宿主
- 酵母菌
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- Human respiratory syncytial virus B
- 宿主
- 酵母菌
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- Canine Distemper Virus (CDV)
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- SDS (SDS-PAGE: 所列应用)
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Protein
- SDS (SDS-PAGE: 所列应用)
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Latest Publications for our FUS 蛋白
: "Molecular Dissection of FUS Points at Synergistic Effect of Low-Complexity Domains in Toxicity." in: Cell reports, Vol. 24, Issue 3, pp. 529-537.e4, (2018) (PubMed).
: "EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma." in: Nature, Vol. 555, Issue 7696, pp. 387-391, (2018) (PubMed).
: "Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathways." in: Acta neuropathologica, Vol. 132, Issue 2, pp. 175-96, (2016) (PubMed).
: "Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose)." in: Nature communications, Vol. 6, pp. 8088, (2015) (PubMed).
: "ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN." in: Human molecular genetics, Vol. 22, Issue 18, pp. 3690-704, (2013) (PubMed).
: "EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma." in: Nature, Vol. 555, Issue 7696, pp. 387-391, (2018) (PubMed).
: "Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathways." in: Acta neuropathologica, Vol. 132, Issue 2, pp. 175-96, (2016) (PubMed).
: "Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose)." in: Nature communications, Vol. 6, pp. 8088, (2015) (PubMed).
: "ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN." in: Human molecular genetics, Vol. 22, Issue 18, pp. 3690-704, (2013) (PubMed).
Aliases for FUS 蛋白
FUS RNA binding protein (FUS) 蛋白fused in sarcoma (Fus) 蛋白
FUS RNA binding protein (Fus) 蛋白
fused in sarcoma (FUS) 蛋白
ALS6 蛋白
D430004D17Rik 蛋白
D930039C12Rik 蛋白
ETM4 蛋白
FUS/TLS 蛋白
FUS1 蛋白
Fus1 蛋白
HNRNPP2 蛋白
POMP75 蛋白
TLS 蛋白
Tls 蛋白
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