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FUS Protein (AA 1-198, partial) (GST tag)

FUS 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant 95 % ELISA
产品编号 ABIN1608021
发货至: 中国
  • 抗原 See all FUS 蛋白
    FUS (Fused in Sarcoma (FUS))
    蛋白类型
    Recombinant
    产品特性
    AA 1-198, partial
    宿主
    • 3
    • 1
    • 1
    • 1
    • 1
    资源
    • 2
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This FUS protein is labelled with GST tag.
    应用范围
    ELISA
    序列
    MASNDYTQQA TQSYGAYPTQ PGQGYSQQSS QPYGQQSYSG YSQSTDTSGY GQSSYSSYGQ SQNTGYGTQS TPQGYGSTGG YGSSQSSQSS YGQQSSYPGY GQQPAPSSTS GSYGSSSQSS SYGQPQSGSY SQQPSYGGQQ QSYGQQQSYN PPQGYGQQNQ YNSSSGGGGG GGGGGNYGQD QSSMSSGGGS GGGYGNQD
    产品特性
    Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.
    纯度
    95 %
    Top Product
    Discover our top product FUS 蛋白
  • 说明

    The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

    限制
    仅限研究用
  • 状态
    Lyophilized
    浓度
    0.2-2 mg/mL
    缓冲液
    Tris-based buffer, 50 % glycerol
    注意事项
    Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week
    储存条件
    -20 °C
    储存方法
    Store at -20 °C for extended storage, conserve at -20 °C or -80 °C
  • 抗原
    FUS (Fused in Sarcoma (FUS))
    别名
    RNA-binding protein FUS protein (FUS 产品)
    别名
    ALS6 Protein, ETM4 Protein, FUS1 Protein, HNRNPP2 Protein, POMP75 Protein, TLS Protein, D430004D17Rik Protein, D930039C12Rik Protein, Fus1 Protein, Tls Protein, FUS/TLS Protein, FUS RNA binding protein Protein, fused in sarcoma Protein, FUS Protein, Fus Protein
    物质类
    Viral Protein
    背景
    Binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single-stranded DNAs and D-loop formation in superhelical double-stranded DNA. May play a role in maintenance of genomic integrity. Note=A chromosomal aberration involving FUS is found in a patient with malignant myxoid liposarcoma. Translocation t(12,16)(q13,p11) with DDIT3. Note=A chromosomal aberration involving FUS is a cause of acute myeloid leukemia (AML). Translocation t(16,21)(p11,q22) with ERG. Defects in FUS may be a cause of angiomatoid fibrous histiocytoma (AFH) [MIM:612160]. A distinct variant of malignant fibrous histiocytoma that typically occurs in children and adolescents and is manifest by nodular subcutaneous growth. Characteristic microscopic features include lobulated sheets of histiocyte-like cells intimately associated with areas of hemorrhage and cystic pseudovascular spaces, as well as a striking cuffing of inflammatory cells, mimicking a lymph node metastasis. Note=A chromosomal aberration involving FUS is found in a patient with angiomatoid fibrous histiocytoma. Translocation t(12,16)(q13,p11.2) with ATF1 generates a chimeric FUS/ATF1 protein. Defects in FUS are the cause of amyotrophic lateral sclerosis type 6 (ALS6) [MIM:608030]. ALS6 is a familial form of amyotrophic lateral sclerosis. ALS is a neurodegenerative disorder affecting upper motor neurons in the brain and lower motor neurons in the brain stem and spinal cord, resulting in fatal paralysis. Sensory abnormalities are absent. Death usually occurs within 2 to 5 years. The etiology of amyotrophic lateral sclerosis is likely to be multifactorial, involving both genetic and environmental factors. The disease is inherited in 5-10%.
    分子量
    47.5 kD
    UniProt
    P35637
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