PDGFB Protein (partial) (AVI tag,His tag)
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- 抗原 See all PDGFB 蛋白
- PDGFB (Platelet Derived Growth Factor Subunit B (PDGFB))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- partial
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This PDGFB protein is labelled with AVI tag,His tag.
- 应用范围
- Western Blotting (WB), ELISA
- 序列
- Ser 82 - Thr 190
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Endotoxin level is less than 1.0 EU per ug by the LAL method.
- Biological Activity Comment
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Measured by its binding ability in a functional ELISA. Immobilized Human PDGF-BB, His Tag at 5 μg/mL (100 μL/well) can bind Human PDGF R beta, Fc Tag with a linear range of 0.02-1.2 μg/mL (QC tested).
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- Discover our top product PDGFB 蛋白
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Platelet Derived Growth Factor Subunit B (PDGFB) (Active) protein
PDGFB 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Platelet Derived Growth Factor Subunit B (PDGFB) (AA 82-190) protein (GST tag)PDGFB 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Platelet Derived Growth Factor Subunit B (PDGFB) (AA 82-190) protein (His tag)PDGFB 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Platelet Derived Growth Factor Subunit B (PDGFB) (AA 82-190) (Active) protein (His tag,AVI tag)PDGFB 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE. Active
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- 应用备注
- This recombinant protein can be used for E, WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- 0.085 % TFA in 30 % ACN
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.
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- 抗原
- PDGFB (Platelet Derived Growth Factor Subunit B (PDGFB))
- 别名
- PDGF-B (PDGFB 产品)
- 别名
- PDGF-2 Protein, PDGF2 Protein, SIS Protein, SSV Protein, c-sis Protein, pdgf2 Protein, sis Protein, si:ch211-79m20.1 Protein, si:dkey-261d11.1 Protein, PDGF-B Protein, Sis Protein, platelet derived growth factor subunit B Protein, platelet-derived growth factor beta polypeptide Protein, platelet derived growth factor subunit B S homeolog Protein, platelet-derived growth factor beta polypeptide a Protein, platelet derived growth factor, B polypeptide Protein, PDGFB Protein, pdgfb.S Protein, pdgfba Protein, Pdgfb Protein
- 背景
- PDGFs are mitogenic during early developmental stages, driving the proliferation of undifferentiated mesenchyme and some progenitor populations. During later maturation stages, PDGF signalling has been implicated in tissue remodelling and cellular differentiation, and in inductive events involved in patterning and morphogenesis. In addition to driving mesenchymal proliferation, PDGFs have been shown to direct the migration, differentiation and function of a variety of specialised mesenchymal and migratory cell types, both during development and in the adult animal. Other growth factors in this family include vascular endothelial growth factors B and C (VEGF-B, VEGF-C)which are active in angiogenesis and endothelial cell growth, and placenta growth factor (PlGF) which is also active in angiogenesis. PDGF plays a role in embryonic development, cell proliferation, cell migration, and angiogenesis. PDGF is a required element in cellular division for fibroblast, a type of connective tissue cell. PDGF is also known to maintain proliferation of oligodendrocyte progenitor cells. Platelet-derived growth factor subunit B is also known as PDGFB, FLJ12858, PDGF2, SIS, SSV, c-sis, is a member of the platelet-derived growth factor family. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.
- 分子量
- 15 kDa
- 基因ID
- 5155
- UniProt
- P01127
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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