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PDGFB Protein (AA 74-182) (His tag)

PDGFB 宿主: 大鼠 宿主: 大肠杆菌(E. Coli) Recombinant >85 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505479
发货至: 中国
  • 抗原 See all PDGFB 蛋白
    PDGFB (Platelet Derived Growth Factor Subunit B (PDGFB))
    蛋白类型
    Recombinant
    产品特性
    AA 74-182
    宿主
    • 13
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    大鼠
    资源
    • 19
    • 4
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This PDGFB protein is labelled with His tag.
    序列
    Ser74-Thr182
    产品特性
    A DNA sequence encoding the Rat PDGF-B (Q05028-1) (Ser74-Thr182) was expressed with a polyhistidine tag at the N-terminus.
    纯度
    >85 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product PDGFB 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    PDGFB (Platelet Derived Growth Factor Subunit B (PDGFB))
    别名
    PDGF-B (PDGFB 产品)
    别名
    PDGF-2 Protein, PDGF2 Protein, SIS Protein, SSV Protein, c-sis Protein, pdgf2 Protein, sis Protein, si:ch211-79m20.1 Protein, si:dkey-261d11.1 Protein, PDGF-B Protein, Sis Protein, platelet derived growth factor subunit B Protein, platelet-derived growth factor beta polypeptide Protein, platelet derived growth factor subunit B S homeolog Protein, platelet-derived growth factor beta polypeptide a Protein, platelet derived growth factor, B polypeptide Protein, PDGFB Protein, pdgfb.S Protein, pdgfba Protein, Pdgfb Protein
    背景

    Background: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

    Synonym: Becaplermin,PDGF 2,PDGF B chain,PDGF subunit B,PDGF-2,PDGF2,Pdgfb,PDGFB,Platelet derived growth factor 2,Platelet-derived growth factor B chain,Platelet-derived growth factor beta polypeptide,Platelet-derived growth factor subunit B,Proto-oncogene c-Sis,SIS,SSV

    分子量
    12.2 kDa
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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