PDGFB 蛋白
(Platelet Derived Growth Factor Subunit B (PDGFB))
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2013].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| PDGFB 蛋白 | 人 | 大肠杆菌（E. Coli） |
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| PDGFB Protein (AA 82-190) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| PDGFB Protein (AA 82-190) (GST tag) | 人 | 小麦胚 |
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| PDGFB Protein (AA 82-190) (His tag) | 小鼠 | 大肠杆菌（E. Coli） |
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| PDGFB Protein (AA 82-190) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| PDGFB Protein (AA 82-190) (His tag) | 小鼠 | 大肠杆菌（E. Coli） |
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| PDGFB Protein (AA 82-242) (His tag) | 犬 | Mammalian Cells |
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| PDGFB Protein (AA 74-182) (His tag) | 大鼠 | 大肠杆菌（E. Coli） |
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| PDGFB Protein (AA 99-330) (Fc Tag) | 人 | HEK-293 Cells |
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| PDGFB Protein (AA 82-190) (His tag) | 小鼠 | 大肠杆菌（E. Coli） |
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| PDGFB Protein (AA 82-190, full length) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| PDGFB Protein (His tag) | Pig | 大肠杆菌（E. Coli） |
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| PDGFB Protein (AA 74-182) (His tag) | 大鼠 | 大肠杆菌（E. Coli） |
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| PDGFB Protein (AA 21-241) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| PDGFB Protein (AA 13-241) (His tag) | 大鼠 | 大肠杆菌（E. Coli） |
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| PDGFB Protein (AA 21-241) | 人 | 大肠杆菌（E. Coli） |
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| PDGFB Protein (AA 82-190) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| Rockland Original | PDGFB 蛋白 | 人 | 大肠杆菌（E. Coli） |
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| PDGFB Protein (AA 82-190) (His tag,AVI tag) | 人 | 大肠杆菌（E. Coli） |
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| Rockland Original | PDGFB 蛋白 | 人 | 大肠杆菌（E. Coli） |
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Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
Protein
- WB (Western Blotting: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 %
Protein
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- 犬
- 宿主
- Mammalian Cells
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- 大鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- AM (Affinity Measurement: 所列应用)
- ADA (Antibody Drug Assay: 所列应用)
- IA (Immunoassay: 所列应用)
- ScA (Screening Assay: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Protein
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- Pig
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 %
Protein
- Imm (Immunogen: 所列应用)
- 宿主
- 大鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 85 % as determined by reducing SDS-PAGE.
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 %
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 大鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- AcA (Activity Assay: 所列应用)
- CC (Cell Culture: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 %
- 生物活性
- Active
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 %
Rockland Original
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- >95 % as determined by SDS-PAGE.
- 生物活性
- Active
Rockland Original
Latest Publications for our PDGFB 蛋白
: "Expression and purification of functional PDGF receptor beta." in: Biochemical and biophysical research communications, Vol. 489, Issue 3, pp. 353-359, (2017) (PubMed).
: "Astragaloside IV inhibits platelet-derived growth factor-BB-stimulated proliferation and migration of vascular smooth muscle cells via the inhibition of p38 MAPK signaling." in: Experimental and therapeutic medicine, Vol. 8, Issue 4, pp. 1253-1258, (2014) (PubMed).
: "Astragaloside IV inhibits platelet-derived growth factor-BB-stimulated proliferation and migration of vascular smooth muscle cells via the inhibition of p38 MAPK signaling." in: Experimental and therapeutic medicine, Vol. 8, Issue 4, pp. 1253-1258, (2014) (PubMed).
Aliases for PDGFB 蛋白
platelet derived growth factor subunit B (PDGFB) 蛋白platelet-derived growth factor beta polypeptide (PDGFB) 蛋白
platelet derived growth factor subunit B S homeolog (pdgfb.S) 蛋白
platelet-derived growth factor beta polypeptide a (pdgfba) 蛋白
platelet derived growth factor, B polypeptide (Pdgfb) 蛋白
platelet derived growth factor subunit B (Pdgfb) 蛋白
c-sis 蛋白
PDGF-2 蛋白
PDGF-B 蛋白
PDGF2 蛋白
pdgf2 蛋白
si:ch211-79m20.1 蛋白
si:dkey-261d11.1 蛋白
SIS 蛋白
sis 蛋白
Sis 蛋白
SSV 蛋白
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