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TNFSF9 Protein (AA 85-254, Soluble) (Fc Tag)
TNFSF9
宿主: 人
宿主: HEK-293 Cells
Recombinant
>90 % (SDS-PAGE)
SDS
产品细节
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TNFSF9
(Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
蛋白类型
Recombinant
产品特性
AA 85-254, Soluble
宿主
All origins for TNFSF9 蛋白
人
资源
All sources for TNFSF9 蛋白
HEK-293 Cells
标记
This TNFSF9 protein is labelled with Fc Tag.
应用范围
SDS-PAGE (SDS)
特异性
Binds to human CD137 receptor.
交叉反应
人
产品特性
The receptor-binding domain of human CD137L (aa 85-254) is fused at the N-terminus to the Fc portion of human IgG1.
纯度
>90 % (SDS-PAGE)
内毒素水平
<0.01EU/μg purified protein (LAL test, Lonza).
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Solid
浓度
Lot specific
缓冲液
Lyophilized. Contains PBS.
储存条件
4 °C,-20 °C
储存方法
Short Term Storage: +4°C Long Term Storage: -20°C Stable for at least 6 months after receipt when stored at -20°C.
有效期
6 months
目标详细情况
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TNFSF9
(Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
别名
CD137L (TNFSF9 产品 )
别名
TNFSF9 Protein, 4-1BB-L Protein, 4-1BBL Protein, AI848817 Protein, Cd137l Protein, Ly63l Protein, CD137L Protein, TNF superfamily member 9 Protein, tumor necrosis factor (ligand) superfamily, member 9 Protein, Tnfsf9 Protein, LOC476729 Protein, TNFSF9 Protein
背景
The CD137 ligand (CD137L, 4-1BBL) is a member of the tumor necrosis factor (TNF) family. CD137L is a type II transmembrane protein found on activated macrophages, dendritic cells and mature B cells. The interaction with its receptor 4-1BB induces recruitment of TNF receptor-associated factor 1 (TRAF1) and TRAF2 and interaction with the kinase p56lck. CD137 and CD137L have been reported to be involved in tumor rejection, apoptosis, anti-viral immunity, diabetes and in T and B cell co-stimulation and modulation of the immune response.
分子量
~46kDa (SDS-PAGE)
UniProt
P41273
途径
Activated T Cell Proliferation , Cancer Immune Checkpoints
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TNFSF9 蛋白
TNFSF9 Protein (AA 85-254, Soluble) (Fc Tag) (ABIN5564465)