DLL4 Protein (AA 1-529, Extracellular Domain) (Fc Tag)
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- 抗原 See all DLL4 蛋白
- DLL4 (delta-Like 4 (DLL4))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 1-529, Extracellular Domain
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This DLL4 protein is labelled with Fc Tag.
- 应用范围
- SDS-PAGE (SDS)
- 特异性
- Interacts with human Notch1 (as confirmed by flow cytometry).
- 交叉反应
- 人
- 产品特性
- Signal peptide and extracellular domain of human DLL4 (aa 1-529) are fused at the C-terminus to the Fc portion of human IgG1.
- 纯度
- >95 % (SDS-PAGE)
- 内毒素水平
- <0.01EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product DLL4 蛋白
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delta-Like 4 (DLL4) (AA 27-524) protein (His-Avi Tag,Biotin)
DLL4 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
delta-Like 4 (DLL4) (AA 27-524) protein (Fc Tag)DLL4 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
delta-Like 4 (DLL4) (AA 558-685) protein (His-IF2DI Tag)DLL4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA
delta-Like 4 (DLL4) (AA 123-221) protein (GST tag)DLL4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
delta-Like 4 (DLL4) (Active) protein (His tag)DLL4 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 96 % as determined by SDS-PAGE Active
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Inhibits adipogenesis of 3T3L-1 cells and mesenchymal stem cells (MSCs). Induces the Notch target gene HES-1 when coated on a plate at 1μg/ml.
- 限制
- 仅限研究用
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- 状态
- Solid
- 浓度
- Lot specific
- 缓冲液
- Lyophilized. Contains PBS + 0.5 % Trehalose.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - 有效期
- 6 months
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- 抗原
- DLL4 (delta-Like 4 (DLL4))
- 别名
- DLL4 (DLL4 产品)
- 别名
- hdelta2 Protein, Delta4 Protein, si:ch211-244p18.5 Protein, zgc:136596 Protein, delta like canonical Notch ligand 4 Protein, delta-like 4 (Drosophila) Protein, DLL4 Protein, Dll4 Protein, dll4 Protein
- 背景
- The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, promoting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.
- 分子量
- ~80kDa (SDS-PAGE)
- UniProt
- Q9NR61
- 途径
- Notch Signaling
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