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DLL4 Protein (AA 1-532, Extracellular Domain) (Fc Tag)

DLL4 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >90 % (SDS-PAGE) SDS Active
产品编号 ABIN1344207
发货至: 中国
  • 抗原 See all DLL4 蛋白
    DLL4 (delta-Like 4 (DLL4))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    Extracellular Domain, AA 1-532
    宿主
    • 13
    • 4
    • 3
    小鼠
    资源
    • 8
    • 5
    • 5
    • 1
    • 1
    HEK-293 Cells
    标记
    This DLL4 protein is labelled with Fc Tag.
    应用范围
    SDS-PAGE (SDS)
    交叉反应
    小鼠
    产品特性
    Signal peptide and extracellular domain of mouse DLL4 (aa 1-532) is fused at the C-terminus to the Fc portion of human IgG1.
    纯度
    >90 % (SDS-PAGE)
    过滤
    0.2 μm filtered
    内毒素水平
    <0.1EU/μg purified protein (LAL test, Lonza).
    Top Product
    Discover our top product DLL4 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    Inhibits adipogenesis of 3T3L-1 cells.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    0.2μm-filtered solution in PBS.
    储存条件
    4 °C,-20 °C
    储存方法
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Working aliquots are stable for up to 3 months when stored at -20°C.
    有效期
    3 months
  • 抗原
    DLL4 (delta-Like 4 (DLL4))
    别名
    DLL4 (DLL4 产品)
    别名
    hdelta2 Protein, Delta4 Protein, si:ch211-244p18.5 Protein, zgc:136596 Protein, delta like canonical Notch ligand 4 Protein, delta-like 4 (Drosophila) Protein, DLL4 Protein, Dll4 Protein, dll4 Protein
    背景
    The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, pro-moting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.
    分子量
    ~95kDa (SDS-PAGE)
    UniProt
    Q9JI71
    途径
    Notch Signaling
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