NFKBIA Protein (Myc-DYKDDDDK Tag)
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- 抗原 See all NFKBIA 蛋白
- NFKBIA (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This NFKBIA protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human NFKBIA / IKBA protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NFKBIA 蛋白
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- NFKBIA (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA))
- 别名
- Nfkbia,ikba (NFKBIA 产品)
- 别名
- IKBA Protein, MAD-3 Protein, NFKBI Protein, AI462015 Protein, Nfkbi Protein, RL/IF-1 Protein, ECI-6/IKBA Protein, NFKBIA Protein, ikbaB Protein, wu:fb81f08 Protein, zgc:56666 Protein, zgc:77616 Protein, ikbaA Protein, wu:fj16a07 Protein, zgc:85769 Protein, NFKB inhibitor alpha Protein, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha Protein, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b Protein, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a Protein, NFKBIA Protein, Nfkbia Protein, nfkbiab Protein, nfkbiaa Protein
- 背景
- This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.
- 分子量
- 35.4 kDa
- NCBI登录号
- NP_065390
- 途径
- NF-kappaB Signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Maintenance of Protein Location, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, BCR Signaling
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