MKNK2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- 抗原 See all MKNK2 蛋白
- MKNK2 (MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 2
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This MKNK2 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human MKNK2 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product MKNK2 蛋白
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MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2) (AA 1-465) protein (Strep Tag)
Crystallography grade MKNK2 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2) (Thr379Asp-Mutant) (Active) protein (GST tag)MKNK2 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2) (AA 1-158) protein (GST tag)MKNK2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2) (AA 41-158) protein (GST tag)MKNK2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2) (AA 1-459) protein (Strep Tag)Crystallography grade MKNK2 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2) protein (His tag)MKNK2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- MKNK2 (MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2))
- 别名
- Mknk2 (MKNK2 产品)
- 别名
- GPRK7 Protein, MNK2 Protein, gprk7 Protein, mnk2 Protein, 2010016G11Rik Protein, Gprk7 Protein, Mnk2 Protein, mknk2 Protein, wu:fb37e05 Protein, wz5090 Protein, fi34c11 Protein, wu:fi34c11 Protein, wu:fi41e12 Protein, zgc:55587 Protein, MAP kinase interacting serine/threonine kinase 2 Protein, MAP kinase-interacting serine/threonine kinase 2 Protein, MAP kinase interacting serine/threonine kinase 2b Protein, MAP kinase interacting serine/threonine kinase 2 L homeolog Protein, MAP kinase interacting serine/threonine kinase 2a Protein, MKNK2 Protein, mknk2 Protein, Mknk2 Protein, mknk2b Protein, mknk2.L Protein, mknk2a Protein
- 背景
- This gene encodes a member of the calcium/calmodulin-dependent protein kinases (CAMK) Ser/Thr protein kinase family, which belongs to the protein kinase superfamily. This protein contains conserved DLG (asp-leu-gly) and ENIL (glu-asn-ile-leu) motifs, and an N-terminal polybasic region which binds importin A and the translation factor scaffold protein eukaryotic initiation factor 4G (eIF4G). This protein is one of the downstream kinases activated by mitogen-activated protein (MAP) kinases. It phosphorylates the eukaryotic initiation factor 4E (eIF4E), thus playing important roles in the initiation of mRNA translation, oncogenic transformation and malignant cell proliferation. In addition to eIF4E, this protein also interacts with von Hippel-Lindau tumor suppressor (VHL), ring-box 1 (Rbx1) and Cullin2 (Cul2), which are all components of the CBC(VHL) ubiquitin ligase E3 complex. Multiple alternatively spliced transcript variants have been found, but the full-length nature and biological activity of only two variants are determined. These two variants encode distinct isoforms which differ in activity and regulation, and in subcellular localization.
- 分子量
- 51.7 kDa
- NCBI登录号
- NP_951009
- 途径
- MAPK Pathway
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