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MKNK2 蛋白

(MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2))

This gene encodes a member of the calcium/calmodulin-dependent protein kinases (CAMK) Ser/Thr protein kinase family, which belongs to the protein kinase superfamily. This protein contains conserved DLG (asp-leu-gly) and ENIL (glu-asn-ile-leu) motifs, and an N-terminal polybasic region which binds importin A and the translation factor scaffold protein eukaryotic initiation factor 4G (eIF4G). This protein is one of the downstream kinases activated by mitogen-activated protein (MAP) kinases. It phosphorylates the eukaryotic initiation factor 4E (eIF4E), thus playing important roles in the initiation of mRNA translation, oncogenic transformation and malignant cell proliferation. In addition to eIF4E, this protein also interacts with von Hippel-Lindau tumor suppressor (VHL), ring-box 1 (Rbx1) and Cullin2 (Cul2), which are all components of the CBC(VHL) ubiquitin ligase E3 complex. Multiple alternatively spliced transcript variants have been found, but the full-length nature and biological activity of only two variants are determined. These two variants encode distinct isoforms which differ in activity and regulation, and in subcellular localization. [provided by RefSeq, Aug 2011].

recommended

MKNK2 Protein (AA 1-465) (Strep Tag) (ABIN3093826)

Crystallography grade MKNK2 宿主: 人宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS

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recommended

MKNK2 Protein (Thr379Asp-Mutant) (GST tag) (ABIN5570743)

MKNK2 宿主: 人宿主: Insect cells (Sf21) Recombinant SDS, Func Active

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recommended

MKNK2 Protein (AA 1-158) (GST tag) (ABIN1310978)

MKNK2 宿主: 人宿主: 小麦胚 Recombinant ELISA, WB, AP, AA

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MKNK2 蛋白 by Grade

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Find MKNK2 蛋白 for a variety of species such as anti-Human MKNK2, anti-Mouse MKNK2, anti-Rat MKNK2. The species listed below are among those available. Click on a link to go to the corresponding products.

MKNK2 蛋白 by Source

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MKNK2 蛋白 by 蛋白类型

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MKNK2 蛋白 by 生物活性

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Popular MKNK2 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

MKNK2 Protein (AA 1-465) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3093826

Quantity 1 mg

Datasheet Datasheet

MKNK2 Protein (Thr379Asp-Mutant) (GST tag)

Reactivity Human

Source Insect cells (Sf21)

Validations

Cat. No. ABIN5570743

Quantity 5 μg

Datasheet Datasheet

MKNK2 Protein (AA 1-158) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1310978

Quantity 10 μg

Datasheet Datasheet

MKNK2 Protein (AA 41-158) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1310980

Quantity 10 μg

Datasheet Datasheet

MKNK2 Protein (AA 1-459) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3136414

Quantity 1 mg

Datasheet Datasheet

MKNK2 Protein (GST tag)

Reactivity Human

Source Insect Cells

Validations

Cat. No. ABIN5509021

Quantity 10 μg

Datasheet Datasheet

MKNK2 Protein (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN2726085

Quantity 50 μg

Datasheet Datasheet

MKNK2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2726084

Quantity 20 μg

Datasheet Datasheet

MKNK2 Protein (AA 1-459) (His tag)

Reactivity Rat

Source Yeast

Validations

Cat. No. ABIN1635067

Quantity 1 mg

Datasheet Datasheet

MKNK2 Protein (AA 1-467) (His tag)

Reactivity Xenopus laevis

Source Yeast

Validations

Cat. No. ABIN1674333

Quantity 1 mg

Datasheet Datasheet

Aliases for MKNK2 蛋白

MAP kinase interacting serine/threonine kinase 2 (MKNK2) 蛋白
MAP kinase interacting serine/threonine kinase 2 (mknk2) 蛋白
MAP kinase-interacting serine/threonine kinase 2 (Mknk2) 蛋白
MAP kinase interacting serine/threonine kinase 2b (mknk2b) 蛋白
MAP kinase interacting serine/threonine kinase 2 L homeolog (mknk2.L) 蛋白
MAP kinase interacting serine/threonine kinase 2 (Mknk2) 蛋白
MAP kinase interacting serine/threonine kinase 2a (mknk2a) 蛋白
2010016G11Rik 蛋白
fi34c11 蛋白
GPRK7 蛋白
gprk7 蛋白
Gprk7 蛋白
mknk2 蛋白
MNK2 蛋白
mnk2 蛋白
Mnk2 蛋白
wu:fb37e05 蛋白
wu:fi34c11 蛋白
wu:fi41e12 蛋白
wz5090 蛋白
zgc:55587 蛋白

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Aliases for MKNK2 蛋白

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