MAP2K3 Protein (Transcript Variant A) (Myc-DYKDDDDK Tag)
-
- 抗原 See all MAP2K3 蛋白
- MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant A
-
宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This MAP2K3 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
-
- Recombinant human MAP2K3 (transcript variant A) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product MAP2K3 蛋白
-
Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (AA 1-347) (Active) protein (GST tag)
MAP2K3 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (AA 20-347) protein (His tag)MAP2K3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (AA 1-100) protein (GST tag)MAP2K3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (AA 1-318) protein (His tag)MAP2K3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS
Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (AA 1-347) protein (Strep Tag)Crystallography grade MAP2K3 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (AA 1-347) protein (Strep Tag)Crystallography grade MAP2K3 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (AA 1-347), (full length) protein (His-SUMO Tag)MAP2K3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (Transcript Variant B) protein (Myc-DYKDDDDK Tag)MAP2K3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- 应用备注
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
-
The tag is located at the C-terminal.
- 限制
- 仅限研究用
-
- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- 抗原
- MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))
- 别名
- Map2k3 (MAP2K3 产品)
- 别名
- MAPKK3 Protein, MEK3 Protein, MKK3 Protein, PRKMK3 Protein, SAPKK-2 Protein, SAPKK2 Protein, AW212142 Protein, Prkmk3 Protein, mMKK3b Protein, Mkk3 Protein, mitogen-activated protein kinase kinase 3 Protein, mitogen activated protein kinase kinase 3 Protein, MAP kinase activator XMEK3 Protein, MAP2K3 Protein, Map2k3 Protein, map2k3 Protein
- 背景
- The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene.
- 分子量
- 36 kDa
- NCBI登录号
- NP_002747
- 途径
- MAPK Pathway, TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2
-
