FADD Protein (Myc-DYKDDDDK Tag)
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- 抗原 See all FADD 蛋白
- FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This FADD protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human FADD protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
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- Discover our top product FADD 蛋白
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Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 109-208) protein (GST tag)
FADD 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-208) protein (GST tag)FADD 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS - PAGE SDS
Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-208) protein (GST tag)FADD 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-208) protein (Strep Tag)Crystallography grade FADD 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-205) protein (Strep Tag)Crystallography grade FADD 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Fas (TNFRSF6)-Associated Via Death Domain (FADD) proteinFADD 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS, WB, ELISA, IP
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
- 别名
- Fadd (FADD 产品)
- 别名
- MORT1 Protein, Mort1/FADD Protein, Mort1 Protein, TNFRSF6 Protein, adaptor Protein, fadd Protein, mort1 Protein, xfadd Protein, Fas associated via death domain Protein, Fas (TNFRSF6)-associated via death domain Protein, Fas associated via death domain S homeolog Protein, Fas (tnfrsf6)-associated via death domain Protein, FADD Protein, Fadd Protein, fadd.S Protein, fadd Protein
- 背景
- The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.
- 分子量
- 23.1 kDa
- NCBI登录号
- NP_003815
- 途径
- Apoptosis, TLR signaling, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
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