FADD 蛋白
(Fas (TNFRSF6)-Associated Via Death Domain (FADD))
The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008].
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custom-made
FADD
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, WB, ELISA
custom-made
FADD
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, WB, ELISA
Rockland Original
Latest Publications for our FADD 蛋白
: "Opioid receptor agonists enhance the phosphorylation state of Fas-associated death domain (FADD) protein in the rat brain: functional interactions with casein kinase Ialpha, Galpha(i) proteins, and ..." in: Neuropharmacology, Vol. 55, Issue 5, pp. 886-99, (2008) (PubMed).
Aliases for FADD 蛋白
Fas associated via death domain (FADD) 蛋白Fas (TNFRSF6)-associated via death domain (Fadd) 蛋白
Fas associated via death domain (Fadd) 蛋白
Fas associated via death domain S homeolog (fadd.S) 蛋白
Fas (tnfrsf6)-associated via death domain (fadd) 蛋白
adaptor 蛋白
fadd 蛋白
MORT1 蛋白
Mort1 蛋白
mort1 蛋白
Mort1/FADD 蛋白
TNFRSF6 蛋白
xfadd 蛋白
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