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BAD Protein (His tag)

BAD 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2715202
发货至: 中国
  • 抗原 See all BAD 蛋白
    BAD (BCL2-Associated Agonist of Cell Death (BAD))
    蛋白类型
    Recombinant
    宿主
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    大肠杆菌(E. Coli)
    标记
    This BAD protein is labelled with His tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human Bcl-2-like 8 (full length, N-term HIS tag, transcript variant 2) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product BAD 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the N-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    BAD (BCL2-Associated Agonist of Cell Death (BAD))
    别名
    Bcl-2-Like 8 (BAD 产品)
    别名
    bad Protein, fa01b12 Protein, wu:fa01b12 Protein, wu:fa96d04 Protein, BAD Protein, BBC2 Protein, BCL2L8 Protein, AI325008 Protein, Bbc2 Protein, BCL2-associated agonist of cell death b Protein, BCL2 associated agonist of cell death Protein, BCL2-associated agonist of cell death Protein, badb Protein, BAD Protein, Bad Protein
    背景
    The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
    分子量
    18.2 kDa
    NCBI登录号
    NP_116784
    途径
    MAPK Pathway, PI3K-Akt Signaling, RTK signaling, Apoptosis, Fc-epsilon Receptor Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events
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