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APEX1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

APEX1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2714786
发货至: 中国
  • 抗原 See all APEX1 蛋白
    APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 2
    宿主
    • 14
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 10
    • 7
    • 4
    • 2
    • 1
    HEK-293 Cells
    标记
    This APEX1 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human APEX1 / REF-1 (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product APEX1 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
    别名
    Apex1,ref-1 (APEX1 产品)
    别名
    apex1 Protein, MGC76280 Protein, MGC79645 Protein, MGC78928 Protein, APE Protein, APE1 Protein, APEN Protein, APEX Protein, APX Protein, HAP1 Protein, REF1 Protein, Apex Protein, REF-1 Protein, BAP1 Protein, apex1a Protein, hm:zehn1532 Protein, wu:fc13d11 Protein, zgc:66204 Protein, Ref-1 Protein, apurinic/apyrimidinic endodeoxyribonuclease 1 Protein, APEX nuclease (multifunctional DNA repair enzyme) 1 Protein, APEX nuclease (multifunctional DNA repair enzyme) 1 L homeolog Protein, DNA-(apurinic or apyrimidinic site) lyase Protein, apurinic/apyrimidinic endonuclease 1 Protein, APEX1 Protein, apex1 Protein, apex1.L Protein, CNG03640 Protein, CNH01280 Protein, nth Protein, Spirs_4119 Protein, Palpr_0103 Protein, Apex1 Protein
    背景
    Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene all encode the same protein.
    分子量
    35.4 kDa
    NCBI登录号
    NP_542379
    途径
    DNA Damage Repair, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus
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