APEX1 Protein (AA 1-318) (T7 tag)
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- 抗原 See all APEX1 蛋白
- APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-318
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This APEX1 protein is labelled with T7 tag.
- 应用范围
- SDS-PAGE (SDS)
- 产品特性
- APEX1, 1-318aa, Human, T7 tag, E.coli
- 纯度
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product APEX1 蛋白
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Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 1-318) protein (GST tag)
APEX1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 97-195) protein (His-IF2DI Tag)APEX1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 1-318) protein (His tag)APEX1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 219-318) protein (GST tag)APEX1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 2-318) protein (His tag)Crystallography grade APEX1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 32-318) protein (His tag)Crystallography grade APEX1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 2-317) protein (His tag)Crystallography grade APEX1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 31-317) protein (His tag)Crystallography grade APEX1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/ml (determined by Bradford assay)
- 缓冲液
- Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 2mM DTT, 10% glycerol
- 储存条件
- 4 °C
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- 抗原
- APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
- 别名
- APEX1 (APEX1 产品)
- 别名
- apex1 Protein, MGC76280 Protein, MGC79645 Protein, MGC78928 Protein, APE Protein, APE1 Protein, APEN Protein, APEX Protein, APX Protein, HAP1 Protein, REF1 Protein, Apex Protein, REF-1 Protein, BAP1 Protein, apex1a Protein, hm:zehn1532 Protein, wu:fc13d11 Protein, zgc:66204 Protein, Ref-1 Protein, apurinic/apyrimidinic endodeoxyribonuclease 1 Protein, APEX nuclease (multifunctional DNA repair enzyme) 1 Protein, APEX nuclease (multifunctional DNA repair enzyme) 1 L homeolog Protein, DNA-(apurinic or apyrimidinic site) lyase Protein, apurinic/apyrimidinic endonuclease 1 Protein, APEX1 Protein, apex1 Protein, apex1.L Protein, CNG03640 Protein, CNH01280 Protein, nth Protein, Spirs_4119 Protein, Palpr_0103 Protein, Apex1 Protein
- 背景
- APEX1, also known as REF1 or APE1 (Apurinic / apyrimidinic endonuclease), is responsible for the incision of DNA basic sites during base excision repair. It has also been shown to stimulate the DNA binding activity of numerous transcription factors that are involved in cancer promotion and progression. APEX1 is part of the cellular response to oxidative stress and protects cells from the genotoxic and cytotoxic effect of oxidizing agents. Recombinant human APEX1 protein, fused to T7-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: APEX nuclease (multifunctional DNA repair enzyme) 1, APE, APE1, APEN, APX, HAP1, REF-1, REF1. NCBI no.: AAH19291
- 分子量
- 36.9 kDa (332aa), confirmed by MALDI-TOF
- 途径
- DNA Damage Repair, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus
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