CTNNB1 Protein (Myc-DYKDDDDK Tag)
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- 抗原 See all CTNNB1 蛋白
- CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CTNNB1 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human Catenin beta-1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CTNNB1 蛋白
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))
- 别名
- Catenin beta-1 (CTNNB1 产品)
- 别名
- Jup Protein, LOC100217813 Protein, CTNNB1 Protein, CTNNB Protein, Bfc Protein, Catnb Protein, Mesc Protein, ctnnb Protein, id:ibd2058 Protein, wu:fb73e10 Protein, wu:fi81c06 Protein, wu:fk25h01 Protein, ctnnb1 Protein, CHBCAT Protein, MRD19 Protein, armadillo Protein, beta-catenin Protein, catenin beta 1 Protein, catenin (cadherin associated protein), beta 1 Protein, catenin (cadherin-associated protein), beta 1 Protein, catenin beta 1 S homeolog Protein, catenin beta 1 L homeolog Protein, CTNNB1 Protein, Ctnnb1 Protein, ctnnb1 Protein, ctnnb1.S Protein, ctnnb1.L Protein
- 背景
- The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants.
- 分子量
- 85.3 kDa
- NCBI登录号
- NP_001895
- 途径
- WNT signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Tube Formation, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2
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