CTNNB1 产品
(Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))
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The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Oct 2009].
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Featured CTNNB1 Categories
CTNNB1 抗体
High quality antibodies with extensive validation data.
CTNNB1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
CTNNB1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CTNNB1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IHC (p), FACS, IP, ICC, IHC (fro), ChIP, CUT&RUN, IHC (wm)
Validations
- (8)
- (14)
- (1)
Cat. No.
ABIN2855042
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (6)
- (6)
Cat. No.
ABIN6260494
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, IF, IP
Validations
- (7)
Cat. No.
ABIN7146984
Quantity
100 μg
Datasheet
Datasheet
Recommended CTNNB1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6954436
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6954437
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6954438
Quantity
96 tests
Datasheet
Datasheet
Recommended CTNNB1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1350670
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350672
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Baculovirus infected Insect Cells
Validations
- (1)
Cat. No.
ABIN7194662
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our CTNNB1 Products
: "Acute Intoxication With Alcohol Reduces Trauma-Induced Proinflammatory Response and Barrier Breakdown in the Lung via the Wnt/β-Catenin Signaling Pathway." in: Frontiers in immunology, Vol. 13, pp. 866925, (2022) (PubMed).: "38" in: , Vol. 1363, Issue Nucleic acids research, pp. 28-39, (1991)
: "A new cut&run low volume-urea (LoV-U) protocol optimized for transcriptional co-factors uncovers Wnt/b-catenin tissue-specific genomic targets." in: Development (Cambridge, England), (2022) (PubMed).
: "Identification of candidate lncRNAs and circRNAs regulating WNT3/β-catenin signaling in essential hypertension." in: Aging, Vol. 12, Issue 9, pp. 8261-8288, (2020) (PubMed).
: "Cancer cell-intrinsic function of CD177 in attenuating β-catenin signaling." in: Oncogene, Vol. 39, Issue 14, pp. 2877-2889, (2020) (PubMed).
: "A novel c-Kit/phospho-prohibitin axis enhances ovarian cancer stemness and chemoresistance via Notch3-PBX1 and β-catenin-ABCG2 signaling." in: Journal of biomedical science, Vol. 27, Issue 1, pp. 42, (2020) (PubMed).
: "Hydroxytyrosol as a Promising Ally in the Treatment of Fibromyalgia." in: Nutrients, Vol. 12, Issue 8, (2020) (PubMed).
: "ARRDC3 suppresses colorectal cancer progression through destabilizing the oncoprotein YAP." in: FEBS letters, Vol. 592, Issue 4, pp. 599-609, (2019) (PubMed).
: "Progranulin protects the mouse retina under hypoxic conditions via inhibition of the Toll‑like receptor‑4‑NADPH oxidase 4 signaling pathway." in: Molecular medicine reports, Vol. 19, Issue 1, pp. 382-390, (2019) (PubMed).
: "Clonal evolution patterns in acute myeloid leukemia with NPM1 mutation. ..." in: Nature communications, Vol. 10, Issue 1, pp. 2031, (2019) (PubMed).
Synonyms and alternative names related to CTNNB1
catenin beta 1 (CTNNB1), catenin (cadherin associated protein), beta 1 (Ctnnb1), catenin beta 1 (Ctnnb1), catenin (cadherin-associated protein), beta 1 (ctnnb1), catenin beta 1 S homeolog (ctnnb1.S), catenin beta 1 L homeolog (ctnnb1.L), armadillo, beta-catenin, Bfc, Catnb, CHBCAT, CTNNB, ctnnb, CTNNB1, ctnnb1, id:ibd2058, Jup, LOC100217813, Mesc, MRD19, wu:fb73e10, wu:fi81c06, wu:fk25h01Protein level used designations for CTNNB1
- catenin beta 1 subunit
- catenin beta-1
- beta catenin 1
- catenin (cadherin-associated protein), beta 1, 88kDa
- catenin beta-1-like
- beta-catenin
- catenin (cadherin associated protein), beta 1, 88kDa
- catenin beta
- beta catenin
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