CTLA-4 (Ipilimumab Biosimilar) 抗体
(CTLA-4 (Ipilimumab Biosimilar))
This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008].
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Recommended CTLA-4 (Ipilimumab Biosimilar) 抗体
Synonyms and alternative names related to CTLA-4 (Ipilimumab Biosimilar)
cytotoxic T-lymphocyte associated protein 4 (CTLA4), CD, CD152, CELIAC3, CTLA-4, GRD4, GSE, IDDM12Protein level used designations for CTLA-4 (Ipilimumab Biosimilar)
- CD152 isoform
- celiac disease 3
- cytotoxic T lymphocyte associated antigen 4 short spliced form
- cytotoxic T-lymphocyte antigen 4
- cytotoxic T-lymphocyte protein 4
- cytotoxic T-lymphocyte-associated antigen 4
- cytotoxic T-lymphocyte-associated serine esterase-4
- ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4
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