电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

CTCFL 产品

(CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))
CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured CTCFL Categories

CTCFL 抗体

High quality antibodies with extensive validation data.

CTCFL ELISA试剂盒

Reliable ELISA kits for a wide range of species.

CTCFL 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CTCFL 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7172781
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ChIP, ChIP-seq
Validations
  • (2)
Cat. No. ABIN6971455
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (6)
  • (1)
Cat. No. ABIN129668
Quantity 100 μg
Datasheet Datasheet

Recommended CTCFL ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
  • (1)
Cat. No. ABIN6965537
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN5594143
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6225336
Quantity 96 tests
Datasheet Datasheet

Recommended CTCFL 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122188
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350632
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3091944
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CTCFL Products

Janssen, Moscona, Elchebly, Papadakis, Redpath, Wang, Rubin, van Kempen, Spatz: "BORIS/CTCFL promotes a switch from a proliferative towards an invasive phenotype in melanoma cells." in: Cell death discovery, Vol. 6, pp. 1, (2020) (PubMed).

Freitas, Malheiros, Stávale, Biassi, Zamunér, de Souza Begnami, Soares, Vettore: "Expression of cancer/testis antigens is correlated with improved survival in glioblastoma." in: Oncotarget, Vol. 4, Issue 4, pp. 636-46, (2013) (PubMed).

Rosa-Garrido, Ceballos, Alonso-Lecue, Abraira, Delgado, Gandarillas: "A cell cycle role for the epigenetic factor CTCF-L/BORIS." in: PLoS ONE, Vol. 7, Issue 6, pp. e39371, (2012) (PubMed).

Macaluso, Caracciolo, Rizzo, Sun, Montanari, Russo, Bellipanni, Khalili, Giordano: "Integrating role of T antigen, Rb2/p130, CTCF and BORIS in mediating non-canonical endoplasmic reticulum-dependent death pathways triggered by chronic ER stress in mouse medulloblastoma." in: Cell cycle (Georgetown, Tex.), Vol. 11, Issue 9, pp. 1841-50, (2012) (PubMed).

Fiorentino, Macaluso, Miranda, Montanari, Russo, Bagella, Giordano: "CTCF and BORIS regulate Rb2/p130 gene transcription: a novel mechanism and a new paradigm for understanding the biology of lung cancer." in: Molecular cancer research : MCR, Vol. 9, Issue 2, pp. 225-33, (2011) (PubMed).

Jones, Ogunkolade, Szary, Aarum, Mumin, Patel, Pieri, Sheer: "Widespread expression of BORIS/CTCFL in normal and cancer cells." in: PLoS ONE, Vol. 6, Issue 7, pp. e22399, (2011) (PubMed).

Bhan, Negi, Shao, Glazer, Chuang, Gaykalova, Sun, Sidransky, Ha, Califano: "BORIS binding to the promoters of cancer testis antigens, MAGEA2, MAGEA3, and MAGEA4, is associated with their transcriptional activation in lung cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 13, pp. 4267-76, (2011) (PubMed).

Hines, Bazarov, Mukhopadhyay, Yaswen: "BORIS (CTCFL) is not expressed in most human breast cell lines and high grade breast carcinomas." in: PLoS ONE, Vol. 5, Issue 3, pp. e9738, (2010) (PubMed).

Monk, Hitchins, Hawes: "Differential expression of the embryo/cancer gene ECSA(DPPA2), the cancer/testis gene BORIS and the pluripotency structural gene OCT4, in human preimplantation development." in: Molecular human reproduction, Vol. 14, Issue 6, pp. 347-55, (2008) (PubMed).

Dougherty, Ichim, Liu, Reznik, Min, Ghochikyan, Agadjanyan, Reznik: "Selective apoptosis of breast cancer cells by siRNA targeting of BORIS." in: Biochemical and biophysical research communications, Vol. 370, Issue 1, pp. 109-12, (2008) (PubMed).

Synonyms and alternative names related to CTCFL

CCCTC-binding factor like (CTCFL), CCCTC-binding factor (zinc finger protein)-like (Ctcfl), CCCTC-binding factor like (Ctcfl), BORIS, Boris, CT27, CTCF-T, CTCFL, dJ579F20.2, HMGB1L1, OTTMUSG00000016680

Protein level used designations for CTCFL

  • BORIS-like protein
  • CTCF paralog
  • CTCF-like protein
  • HMG-1L1
  • brother of the regulator of imprinted sites
  • cancer/testis antigen 27
  • putative high mobility group protein 1-like 1
  • putative high mobility group protein B1-like 1
  • transcriptional repressor CTCFL
  • zinc finger protein CTCF-T
  • CCCTC-binding factor (zinc finger protein)-like
  • CCCTC-binding factor-like protein
  • BORIS
  • Brother of the regulator of imprinted sites
  • likely orthologue of H. sapiens CCCTC-binding factor-like protein (CTCFL)
  • brother of regulator of imprinted sites
  • transcriptional repressor CTCFL-like
You are here:
客服