MYD88 Protein (AA 176-280) (His tag,Strep II tag)
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- 抗原 See all MYD88 蛋白
- MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))
- 蛋白类型
- Recombinant
- 产品特性
- AA 176-280
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This MYD88 protein is labelled with His tag,Strep II tag.
- 应用范围
- Western Blotting (WB), ELISA, Mass Spectrometry (MS)
- 纯度
- ~95 %
- Top Product
- Discover our top product MYD88 蛋白
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Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 31-130) protein (GST tag)
MYD88 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 1-296) protein (GST tag)MYD88 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 1-296) protein (Strep Tag)Crystallography grade MYD88 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- 应用备注
- This recombinant protein can be used for WB, ELISA, MS.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 1X PBS containing 0.1 % SDS and 0.02 % NaN
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- 储存条件
- -80 °C
- 储存方法
- Store in working aliquots at -70 °C.
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- 抗原
- MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))
- 别名
- MyD88 (MYD88 产品)
- 别名
- MYD88D Protein, XMyD88 Protein, myd88d Protein, MGC84928 Protein, CG2078 Protein, DMMYD88 Protein, DmMyD88 Protein, DmMyd88 Protein, Dmel\\CG2078 Protein, EP(2)2535 Protein, Kra Protein, LD20892 Protein, MYD88 Protein, MyD88 Protein, Myd88F Protein, dMyD88 Protein, dMyd88 Protein, kra Protein, myd88 Protein, zgc:103541 Protein, GB12344 Protein, NV10640 Protein, myd88-a Protein, myd88-b Protein, myeloid differentiation primary response 88 Protein, myeloid differentiation primary response 88 S homeolog Protein, myeloid differentiation primary response gene 88 Protein, CG2078 gene product from transcript CG2078-RB Protein, myeloid differentiation primary response protein MyD88-A Protein, myeloid differentiation primary response protein MyD88 Protein, myeloid differentiation factor 88 Protein, myeloid differentiation primary response 88 L homeolog Protein, MYD88 Protein, myd88.S Protein, Myd88 Protein, myd88 Protein, LOC413194 Protein, LOC100118553 Protein, LOC575153 Protein, myd88.L Protein
- 背景
- The pro-inflammatory cytokine IL-1 induced cellular response requires IL-1 receptor complex including IL-1RI and IL-1RAcP. MyD88 has been identified as an adapter molecule in the IL-1 signaling pathway (1). MyD88 associates with and recruits IRAK to the IL-1 receptor complex in response to IL-1 treatment and dominant negative form of MyD88 attenuates IL-1R-mediated NF-?B activation. MyD88 is also employed as a regulator molecule by IL-18 receptor and human Toll receptor (2,3), which are members in the Toll/IL-1R family of receptors. Targeted disruption of the MyD88 gene results in lose of cellular responses to IL-1 and IL-18, and MyD88-deficient mice lack responses to bacterial product LPS that employs Toll-like receptors 2 and 4 (TLR2 and TLR4) as the signaling receptors. MyD88 is a general adapter protein for the Toll/IL-1R family of receptors and plays an important role in the inflammatory response induced by cytokines IL-1 and IL-18 and endotoxin. MyD88 gene is expressed in many tissues.
- 分子量
- 15 kDa (Calculated)
- 基因ID
- 4615
- OMIM
- 1814020
- UniProt
- Q99836
- 途径
- NF-kappaB Signaling, TLR signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
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