TNFRSF10A Protein (AA 24-239) (His tag)
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- 抗原 See all TNFRSF10A 蛋白
- TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
- 蛋白类型
- Recombinant
- 产品特性
- AA 24-239
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This TNFRSF10A protein is labelled with His tag.
- 序列
- AA 24-239
- 产品特性
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 24 kDa. The protein migrates as 22-24 kDa under reducing (R) condition (SDS-PAGE).
- 纯度
- >90 % as determined by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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- Discover our top product TNFRSF10A 蛋白
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Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) protein (His-Avi Tag,Biotin)
TNFRSF10A 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) (AA 34-239) protein (Fc Tag)TNFRSF10A 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) protein (His-Avi Tag)TNFRSF10A 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) (AA 103-239) protein (His-DYKDDDDK-Strep II Tag)TNFRSF10A 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) (AA 24-239) protein (Fc Tag)TNFRSF10A 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) protein (His tag)TNFRSF10A 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) (AA 379-445) protein (His-IF2DI Tag)TNFRSF10A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) (AA 105-204) protein (GST tag)TNFRSF10A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) (AA 1-238) proteinTNFRSF10A 宿主: 人 宿主: Human Recombinant SDS
Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) (AA 24-239) protein (His tag)Crystallography grade TNFRSF10A 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
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- 抗原
- TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
- 别名
- TRAIL R1 (TNFRSF10A 产品)
- 别名
- APO2 Protein, CD261 Protein, DR4 Protein, TRAILR-1 Protein, TRAILR1 Protein, TNFRSF10A Protein, TNF receptor superfamily member 10a Protein, tumor necrosis factor receptor superfamily member 26 Protein, tumor necrosis factor receptor superfamily, member 10a Protein, TNFRSF10A Protein, LOC510798 Protein
- 背景
- Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A) is also known as TNF-related apoptosis-inducing ligand receptor 1 (TRAIL-R1), Death receptor 4 (DR4), CD261 and APO2, which belongs to TNF superfamily. TRAILR1 / TNFRSF10A contains 1 death domain and 3 TNFR-Cys repeats. TNFRSF10A / DR4 is widely expressed and high levels are found in spleen, peripheral blood leukocytes, small intestine and thymus, but also in K-562 erythroleukemia cells, MCF-7 breast carcinoma cells and activated T-cells. APO2 / TNFRSF10A is receptor for the cytotoxic ligand TNFSF10 / TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. TRAILR-1 / DR4 / CD261 promotes the activation of NF-kappa-B.
- 分子量
- 24.8 kDa
- NCBI登录号
- NP_003835
- 途径
- Apoptosis, Positive Regulation of Endopeptidase Activity
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