TNFRSF10A Protein (AA 24-239) (Fc Tag)
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Quick Overview for TNFRSF10A Protein (AA 24-239) (Fc Tag) (ABIN2181864)
抗原
See all TNFRSF10A 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 24-239
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标记
- This TNFRSF10A protein is labelled with Fc Tag.
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序列
- AA 24-239
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产品特性
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 49 kDa. The protein migrates as 47-49 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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过滤
- 0.22 μm filtered
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内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) (AA 34-239) (Active) protein (Biotin,His-Avi Tag)
TNFRSF10A 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) (AA 24-239) (Active) protein (hFc Tag)TNFRSF10A 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) (AA 34-239) (Active) protein (His-Avi Tag)TNFRSF10A 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) (AA 103-239) protein (His-DYKDDDDK-Strep II Tag)TNFRSF10A 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) (AA 105-204) protein (GST tag)TNFRSF10A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) protein (His tag)TNFRSF10A 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) (AA 379-445) protein (His-IF2DI Tag)TNFRSF10A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) (AA 24-239) protein (His tag)TNFRSF10A 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 90 % SDS
Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) (AA 24-239) protein (His tag)TNFRSF10A 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 50 mM Tris, 100 mM Glycine, pH 7.5
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注意事项
- Please avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
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: "High-efficiency antibody discovery achieved with multiplexed microscopy." in: Microscopy (Oxford, England), Vol. 65, Issue 4, pp. 341-52, (2018) (PubMed).
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- TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
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别名
- TRAIL R1
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背景
- Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A) is also known as TNF-related apoptosis-inducing ligand receptor 1 (TRAIL-R1), Death receptor 4 (DR4), CD261 and APO2, which belongs to TNF superfamily. TRAILR1 / TNFRSF10A contains 1 death domain and 3 TNFR-Cys repeats. TNFRSF10A / DR4 is widely expressed and high levels are found in spleen, peripheral blood leukocytes, small intestine and thymus, but also in K-562 erythroleukemia cells, MCF-7 breast carcinoma cells and activated T-cells. APO2 / TNFRSF10A is receptor for the cytotoxic ligand TNFSF10 / TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. TRAILR-1 / DR4 / CD261 promotes the activation of NF-kappa-B.
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分子量
- 49.0 kDa
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NCBI登录号
- NP_003835
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途径
- Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
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