EPH Receptor B4 Protein (EPHB4) (AA 16-539) (His tag)
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- 抗原 See all EPH Receptor B4 (EPHB4) 蛋白
- EPH Receptor B4 (EPHB4)
- 蛋白类型
- Recombinant
- 产品特性
- AA 16-539
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This EPH Receptor B4 protein is labelled with His tag.
- 序列
- AA 16-539
- 产品特性
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 57.8 kDa. The protein migrates as 65-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 纯度
- >97 % as determined by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product EPHB4 蛋白
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EPH Receptor B4 (EPHB4) (AA 16-539) protein (His tag)
EPHB4 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
EPH Receptor B4 (EPHB4) (AA 198-323) protein (GST tag)EPHB4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
EPH Receptor B4 (EPHB4) (AA 1-987) protein (GST tag)EPHB4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
EPH Receptor B4 (EPHB4) (Active) protein (Fc Tag)EPHB4 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
EPH Receptor B4 (EPHB4) (AA 563-987) (Active) protein (GST tag,His tag)EPHB4 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 90 % as determined by reducing SDS-PAGE. Active
EPH Receptor B4 (EPHB4) (Active) protein (His tag)EPHB4 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 98 % as determined by SDS-PAGE Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- No activity loss was observed after storage at: 4-8°C for 1 year in lyophilized state 4-8°C for 1 month under sterile conditions after reconstitution -20°C to -70°C for 3 months under sterile conditions after reconstitution
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- 抗原
- EPH Receptor B4 (EPHB4)
- 别名
- EphB4 (EPHB4 产品)
- 别名
- HTK Protein, MYK1 Protein, TYRO11 Protein, htk Protein, myk1 Protein, ephB4a Protein, tyro11 Protein, ephb4b Protein, MGC130997 Protein, AI042935 Protein, Htk Protein, MDK2 Protein, Myk1 Protein, Tyro11 Protein, cb646 Protein, ephB4 Protein, rtk5 Protein, EphB-rtk8 Protein, cb417 Protein, rtk8 Protein, EPH receptor B4 Protein, EPH receptor B4 L homeolog Protein, EPH receptor B4 S homeolog Protein, Eph receptor B4 Protein, eph receptor B4a Protein, eph receptor B4b Protein, EPHB4 Protein, ephb4.L Protein, ephb4.S Protein, ephb4 Protein, Ephb4 Protein, ephb4a Protein, ephb4b Protein
- 背景
- Ephrin type-B receptor 4(EPHB4) is also known as HTK, MYK1 and TYRO11,is a member of Eph family. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by EPHB4 binds to Ephrin-B2 and plays an essential role in vascular development. EPHB4 and its ligand ephrin-B2 are specifically expressed on venous and arterial endothelial cells, respectively, and play an essential role in vascular development via bidirectional signals. The forward EPHB4 signaling inhibits cell adhesion, chemotaxis, angiogenesis and tumor growth. Incontrast, the reverse Ephrin-B2 signaling exerts the opposite effect. It has been reported that aberrant expression of EPHB4 is associated with prostate cancer and highly malignant breast cancers, accordingly, EPHB4 has potential application as a therapeutic candidate.
- 分子量
- 57.9 kDa
- NCBI登录号
- NP_004435
- 途径
- RTK signaling
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