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EPH Receptor B4 Protein (EPHB4) (His tag)

EPHB4 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 98 % as determined by SDS-PAGE Active
产品编号 ABIN7195557
发货至: 中国
  • 抗原 See all EPH Receptor B4 (EPHB4) 蛋白
    EPH Receptor B4 (EPHB4)
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 20
    • 4
    小鼠
    资源
    • 9
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This EPH Receptor B4 protein is labelled with His tag.
    原理
    Recombinant Mouse EphB4/HTK Protein (His Tag)(Active)
    序列
    Met 1-Ala 539
    产品特性
    A DNA sequence encoding the mouse EPHB4 (P54761-1) extracellular domain (Met 1-Ala 539) was fused with a polyhistidine tag at the C-terminus.
    纯度
    > 98 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Biological Activity Comment
    Measured by its binding ability in a functional ELISA. Immobilized mouse EphB4 at 2 μg/ml (100 μl/well) can bind mouse EphrinB2 with a linear range of 0.2-25 ng/ml.
    Top Product
    Discover our top product EPHB4 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    EPH Receptor B4 (EPHB4)
    别名
    EphB4/HTK (EPHB4 产品)
    别名
    HTK Protein, MYK1 Protein, TYRO11 Protein, htk Protein, myk1 Protein, ephB4a Protein, tyro11 Protein, ephb4b Protein, MGC130997 Protein, AI042935 Protein, Htk Protein, MDK2 Protein, Myk1 Protein, Tyro11 Protein, cb646 Protein, ephB4 Protein, rtk5 Protein, EphB-rtk8 Protein, cb417 Protein, rtk8 Protein, EPH receptor B4 Protein, EPH receptor B4 L homeolog Protein, EPH receptor B4 S homeolog Protein, Eph receptor B4 Protein, eph receptor B4a Protein, eph receptor B4b Protein, EPHB4 Protein, ephb4.L Protein, ephb4.S Protein, ephb4 Protein, Ephb4 Protein, ephb4a Protein, ephb4b Protein
    背景

    Background: Ephrin type-B receptor 4 is a protein that in humans is encoded by the EPHB4 gene. It is a single-pass type I membrane protein belonging to the ephrin receptor subfamily of protein kinase superfamily. Members of the ephrin and Eph family are local mediators of cell function through largely contact-dependent processes in development and in maturity. Furthermore, EphB4 protein and the corresponding ligand Ephrin-B2 contribute to tumor growth in various human tumors. EphB4 protein has tumor suppressor activities and that regulation of cell proliferation, extracellular matrix remodeling, and invasive potential are important mechanisms of tumor suppression. Therefore, Ephrin-B2/EphB4 may be recognized as a novel prognostic indicator for cancers.

    Synonym: AI042935,Htk,MDK2,Myk1,Tyro11

    分子量
    59 kDa
    途径
    RTK signaling
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