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MAP3K7 Protein (AA 1-579) (GST tag)

MAP3K7 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA, KAA
产品编号 ABIN1310225
发货至: 中国
  • 抗原 See all MAP3K7 蛋白
    MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))
    蛋白类型
    Recombinant
    产品特性
    AA 1-579
    宿主
    • 4
    • 1
    • 1
    资源
    • 2
    • 1
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    • 1
    小麦胚
    标记
    This MAP3K7 protein is labelled with GST tag.
    应用范围
    ELISA, Western Blotting (WB), Affinity Purification (AP), Antibody Array (AA), Kinase Activity Assay (KAA)
    原理
    MAP3K7 (Human) Recombinant Protein (P01)
    序列
    MSTASAASSS SSSSAGEMIE APSQVLNFEE IDYKEIEVEE VVGRGAFGVV CKAKWRAKDV AIKQIESESE RKAFIVELRQ LSRVNHPNIV KLYGACLNPV CLVMEYAEGG SLYNVLHGAE PLPYYTAAHA MSWCLQCSQG VAYLHSMQPK ALIHRDLKPP NLLLVAGGTV LKICDFGTAC DIQTHMTNNK GSAAWMAPEV FEGSNYSEKC DVFSWGIILW EVITRRKPFD EIGGPAFRIM WAVHNGTRPP LIKNLPKPIE SLMTRCWSKD PSQRPSMEEI VKIMTHLMRY FPGADEPLQY PCQYSDEGQS NSATSTGSFM DIASTNTSNK SDTNMEQVPA TNDTIKRLES KLLKNQAKQQ SESGRLSLGA SRGSSVESLP PTSEGKRMSA DMSEIEARIA ATTGNGQPRR RSIQDLTVTG TEPGQVSSRS SSPSVRMITT SGPTSEKPTR SHPWTPDDST DTNGSDNSIP MAYLTLDHQL QPLAPCPNSK ESMAVFEQHC KMAQEYMKVQ TEIALLLQRK QELVAELDQD EKDQQNTSRL VQEHKKLLDE NKSLSTYYQQ CKKQLEVIRS QQQKRQGTS
    产品特性
    Human MAP3K7 full-length ORF ( AAH17715, 1 a.a. - 579 a.a.) recombinant protein with GST-tag at N-terminal.
    纯化方法
    in vitro wheat germ expression system
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    Preparation method: in vitro, wheat germ expression system
    Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

    限制
    仅限研究用
  • 缓冲液
    50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
    注意事项
    Aliquot to avoid repeated freezing and thawing.
    储存条件
    -80 °C
    储存方法
    Best use within three months from the date of receipt of this protein.
  • Salazar, Kashiwada, Krejci, Meyer, Casale, Hallowell, Wilcox, Donoghue, Thompson: "Fibroblast growth factor receptor 3 interacts with and activates TGF?-activated kinase 1 tyrosine phosphorylation and NF?B signaling in multiple myeloma and bladder cancer." in: PLoS ONE, Vol. 9, Issue 1, pp. e86470, (2014) (PubMed).

    Sorrentino, Thakur, Grimsby, Marcusson, von Bulow, Schuster, Zhang, Heldin, Landström: "The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner." in: Nature cell biology, Vol. 10, Issue 10, pp. 1199-207, (2008) (PubMed).

    Liu, Yao, Li, Wang, Zheng, Cao: "CaMKII promotes TLR-triggered proinflammatory cytokine and type I interferon production by directly binding and activating TAK1 and IRF3 in macrophages." in: Blood, Vol. 112, Issue 13, pp. 4961-70, (2008) (PubMed).

  • 抗原
    MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))
    别名
    MAP3K7 (MAP3K7 产品)
    别名
    si:ch211-225h9.1 Protein, zgc:110612 Protein, Tak1 Protein, MEKK7 Protein, TAK1 Protein, TGF1a Protein, B430101B05 Protein, C87327 Protein, mitogen-activated protein kinase kinase kinase 7 Protein, mitogen activated protein kinase kinase kinase 7 Protein, map3k7 Protein, Map3k7 Protein, MAP3K7 Protein
    背景
    Full Gene Name: mitogen-activated protein kinase kinase kinase 7
    Synonyms: TAK1,TGF1a
    基因ID
    6885
    途径
    NF-kappaB Signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway
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