MAP3K7 蛋白
(Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2\; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| MAP3K7 Protein (AA 1-579) (GST tag) | 人 | 小麦胚 |
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| MAP3K7 Protein (AA 471-579) (GST tag) | 人 | 小麦胚 |
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| MAP3K7 Protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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| MAP3K7 Protein (AA 1-606) (Strep Tag) | 人 | Cell-free protein synthesis (CFPS) |
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| MAP3K7 Protein (AA 1-579) (Strep Tag) | 小鼠 | Cell-free protein synthesis (CFPS) |
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| MAP3K7 Protein (Transcript Variant A) (Myc-DYKDDDDK Tag) | 人 | HEK-293 Cells |
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| MAP3K7 Protein (AA 1-606) (His tag) | 大鼠 | 酵母菌 |
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| MAP3K7 Protein (AA 30-285) (His tag) | 人 | Bacteria |
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| MAP3K7 Protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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Protein
- KAA (Kinase Activity Assay: 有验证图片)
3 references - 宿主
- 人
- 宿主
- 小麦胚
- 蛋白类型
- Recombinant
Protein
- ELISA (ELISA: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Protein
- ELISA (ELISA: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- 质量等级
- custom-made
- 宿主
- 人
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- ELISA (ELISA: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- 质量等级
- custom-made
- 宿主
- 小鼠
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- WB (Western Blotting: 有验证图片)
- AbP (Antibody Production: 所列应用)
- STD (Standard: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Protein
- ELISA (ELISA: 所列应用)
- 宿主
- 大鼠
- 宿主
- 酵母菌
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- ELISA (ELISA: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Latest Publications for our MAP3K7 蛋白
: "Fibroblast growth factor receptor 3 interacts with and activates TGF?-activated kinase 1 tyrosine phosphorylation and NF?B signaling in multiple myeloma and bladder cancer." in: PLoS ONE, Vol. 9, Issue 1, pp. e86470, (2014) (PubMed).
: "The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner." in: Nature cell biology, Vol. 10, Issue 10, pp. 1199-207, (2008) (PubMed).
: "CaMKII promotes TLR-triggered proinflammatory cytokine and type I interferon production by directly binding and activating TAK1 and IRF3 in macrophages." in: Blood, Vol. 112, Issue 13, pp. 4961-70, (2008) (PubMed).
: "The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner." in: Nature cell biology, Vol. 10, Issue 10, pp. 1199-207, (2008) (PubMed).
: "CaMKII promotes TLR-triggered proinflammatory cytokine and type I interferon production by directly binding and activating TAK1 and IRF3 in macrophages." in: Blood, Vol. 112, Issue 13, pp. 4961-70, (2008) (PubMed).
Aliases for MAP3K7 蛋白
mitogen-activated protein kinase kinase kinase 7 (map3k7) 蛋白mitogen activated protein kinase kinase kinase 7 (Map3k7) 蛋白
mitogen-activated protein kinase kinase kinase 7 (MAP3K7) 蛋白
mitogen-activated protein kinase kinase kinase 7 (Map3k7) 蛋白
B430101B05 蛋白
C87327 蛋白
MEKK7 蛋白
si:ch211-225h9.1 蛋白
Tak1 蛋白
TAK1 蛋白
TGF1a 蛋白
zgc:110612 蛋白
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