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UMPS Protein (His tag)

UMPS 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN1098695
发货至: 中国
  • 抗原 See all UMPS 蛋白
    UMPS (Uridine Monophosphate Synthetase (UMPS))
    蛋白类型
    Recombinant
    宿主
    • 6
    • 1
    资源
    • 2
    • 2
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This UMPS protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    纯度
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product UMPS 蛋白
  • 说明

    Synonyms: Uridine 5'-monophosphate synthase, OPRT

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/ml (determined by Bradford assay)
    缓冲液
    20 mM Tris-HCl buffer (pH 8.0) containing 2 M Urea, 20% glycerol
    储存条件
    4 °C
    储存方法
    Avoid repeated freezing and thawing cycles.
  • 抗原
    UMPS (Uridine Monophosphate Synthetase (UMPS))
    别名
    UMPS (UMPS 产品)
    别名
    zgc:55702 Protein, zgc:55723 Protein, UMPS Protein, OPRT Protein, 1700095D23Rik Protein, AA408257 Protein, AL033308 Protein, BB164745 Protein, Orotidine 5'-phosphate decarboxylase Protein, uridine monophosphate synthetase Protein, uridine monophosphate synthetase L homeolog Protein, uridine 5'-monophosphate synthase Protein, umps-1 Protein, umps Protein, umps.L Protein, UMPS Protein, LOC100556619 Protein, Umps Protein
    背景
    Uridine 5'-monophosphate synthase, also known as UMPS, is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. Unlike prokaryotes, UMPS in eukaryotes combines the orotate phosphoribosyltransferase and the orotidine-5’-monophosphate (OMP) decarboxylase activities into a single protein. The union of these two enzymes is thought to stabilize the catalytic centers due to the low molar concentration of the protein in mammalian cells. Defects in this gene are the cause of hereditary orotic aciduria. Recombinant human UMPS protein, fused to His-tag at N-terminus, was expressed in E.coli.
    分子量
    54.3 kDa (500aa)
    NCBI登录号
    NP_000364
    途径
    Ribonucleoside Biosynthetic Process
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