UMPS 蛋白
(Uridine Monophosphate Synthetase (UMPS))
This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010].
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9 results
UMPS
宿主: 小鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 %
SDS, WB, Imm, PC
UMPS
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 %
SDS, WB, Imm, PC
UMPS
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
Latest Publications for our UMPS 蛋白
: "Metabolomics identifies pyrimidine starvation as the mechanism of 5-aminoimidazole-4-carboxamide-1-β-riboside-induced apoptosis in multiple myeloma cells." in: Molecular cancer therapeutics, Vol. 12, Issue 7, pp. 1310-21, (2013) (PubMed).
Aliases for UMPS 蛋白
Orotidine 5'-phosphate decarboxylase (umps-1) 蛋白uridine monophosphate synthetase (umps) 蛋白
uridine monophosphate synthetase L homeolog (umps.L) 蛋白
uridine monophosphate synthetase (UMPS) 蛋白
uridine 5'-monophosphate synthase (LOC100556619) 蛋白
uridine monophosphate synthetase (Umps) 蛋白
1700095D23Rik 蛋白
AA408257 蛋白
AL033308 蛋白
BB164745 蛋白
OPRT 蛋白
UMPS 蛋白
zgc:55702 蛋白
zgc:55723 蛋白
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