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UMPS 蛋白

(Uridine Monophosphate Synthetase (UMPS))
This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010].
UMPS Protein (AA 381-479) (GST tag) UMPS Protein (AA 381-479) (GST tag) UMPS Protein (AA 381-479) (GST tag) (ABIN1324639)

UMPS 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

UMPS Protein (AA 1-480) (GST tag) UMPS Protein (AA 1-480) (GST tag) UMPS Protein (AA 1-480) (GST tag) (ABIN1324637)

UMPS 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

UMPS Protein (AA 2-480) (His tag) UMPS Protein (AA 2-480) (His tag) UMPS Protein (AA 2-480) (His tag) (ABIN3075158)

Crystallography grade UMPS 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys

UMPS 蛋白 by Grade

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UMPS 蛋白 by Origin

Find UMPS 蛋白 for a variety of species such as anti-Human UMPS, anti-Mouse UMPS. The species listed below are among those available. Click on a link to go to the corresponding products.

UMPS 蛋白 by Source

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UMPS 蛋白 by 蛋白类型

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UMPS 蛋白 by 应用范围

Find UMPS 蛋白 validated for a specific application such as WB, SDS, ELISA, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

UMPS 蛋白 by 生物活性

Find UMPS 蛋白 with a specific 生物活性. The 生物活性 listed below are among those available. Click on a link to go to the corresponding products.

Popular UMPS 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324639
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324637
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3075158
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (1)
Cat. No. ABIN2735007
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7418299
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7418362
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
  • (1)
Cat. No. ABIN6388096
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our UMPS 蛋白

Bardeleben, Sharma, Reeve, Bassilian, Frost, Hoang, Shi, Lichtenstein: "Metabolomics identifies pyrimidine starvation as the mechanism of 5-aminoimidazole-4-carboxamide-1-β-riboside-induced apoptosis in multiple myeloma cells." in: Molecular cancer therapeutics, Vol. 12, Issue 7, pp. 1310-21, (2013) (PubMed).

Aliases for UMPS 蛋白

Orotidine 5'-phosphate decarboxylase (umps-1) 蛋白
uridine monophosphate synthetase (umps) 蛋白
uridine monophosphate synthetase L homeolog (umps.L) 蛋白
uridine monophosphate synthetase (UMPS) 蛋白
uridine 5'-monophosphate synthase (LOC100556619) 蛋白
uridine monophosphate synthetase (Umps) 蛋白
1700095D23Rik 蛋白
AA408257 蛋白
AL033308 蛋白
BB164745 蛋白
OPRT 蛋白
UMPS 蛋白
zgc:55702 蛋白
zgc:55723 蛋白
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