ULK3 蛋白
(Unc-51-Like Kinase 3 (ULK3))
Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3). Positively regulates SHH signaling in the mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently. Also acts as a regulator autophagy (By similarity).
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ULK3
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
Aliases for ULK3 蛋白
unc-51 like kinase 3 (ULK3) 蛋白unc-51 like kinase 3 (ulk3) 蛋白
unc-51 like kinase 3 (Ulk3) 蛋白
unc-51 like kinase 3 L homeolog (ulk3.L) 蛋白
unc-51-like kinase 3 (Ulk3) 蛋白
1200015E14Rik 蛋白
zgc:162196 蛋白
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