UHRF2 蛋白
(Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2))
This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding. [provided by RefSeq, Feb 2012].
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UHRF2
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
Aliases for UHRF2 蛋白
ubiquitin like with PHD and ring finger domains 2 (UHRF2) 蛋白ubiquitin-like, containing PHD and RING finger domains 2 (Uhrf2) 蛋白
ubiquitin like with PHD and ring finger domains 2 (Uhrf2) 蛋白
ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase L homeolog (uhrf2.L) 蛋白
2310065A22Rik 蛋白
AI426270 蛋白
AW214556 蛋白
D130071B19Rik 蛋白
NIRF 蛋白
Nirf 蛋白
RNF107 蛋白
URF2 蛋白
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