F11R Protein (AA 28-238) (His tag)
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- 抗原 See all F11R 蛋白
- F11R (F11 Receptor (F11R))
- 蛋白类型
- Recombinant
- 产品特性
- AA 28-238
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宿主
- 人
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资源
- 人细胞
- 标记
- This F11R protein is labelled with His tag.
- 原理
- Recombinant Human Junctional Adhesion Molecule A/JAM-A/CD321 (C-6His)
- 序列
- SVTVHSSEPE VRIPENNPVK LSCAYSGFSS PRVEWKFDQG DTTRLVCYNN KITASYEDRV TFLPTGITFK SVTREDTGTY TCMVSEEGGN SYGEVKVKLI VLVPPSKPTV NIPSSATIGN RAVLTCSEQD GSPPSEYTWF KDGIVMPTNP KSTRAFSNSS YVLNPTTGEL VFDPLSASDT GEYSCEARNG YGTPMTSNAV RMEAVERNVG VDHHHHHH
- 产品特性
- Recombinant Human Junctional Adhesion Molecule A/JAM-A produced by transfected human cells is a secreted protein with sequence (Ser28-Val238) of Human JAM-A fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product F11R 蛋白
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F11 Receptor (F11R) (AA 28-238) protein (His tag)
F11R 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
F11 Receptor (F11R) (AA 27-238) protein (His tag)F11R 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
F11 Receptor (F11R) (AA 26-238) protein (His tag)F11R 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
F11 Receptor (F11R) protein (His tag)F11R 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > (23.7+75.2) % as determined by SDS-PAGE
F11 Receptor (F11R) (AA 1-299) protein (GST tag)F11R 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
F11 Receptor (F11R) protein (Fc Tag)F11R 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 94 % as determined by SDS-PAGE
F11 Receptor (F11R) protein (Fc Tag)F11R 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 96 % as determined by SDS-PAGE
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 50 mM NaCl, 100 mM Glycine, pH 7.5.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - 有效期
- 3 months
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- 抗原
- F11R (F11 Receptor (F11R))
- 别名
- jam-a (F11R 产品)
- 别名
- CD321 Protein, JAM Protein, JAM1 Protein, JAMA Protein, JCAM Protein, KAT Protein, PAM-1 Protein, 9130004G24 Protein, AA638916 Protein, ESTM33 Protein, JAM-1 Protein, JAM-A Protein, Jcam Protein, Jcam1 Protein, Ly106 Protein, Jam1 Protein, F11 receptor Protein, F11R Protein, F11r Protein
- Sub Type
- Fusionprotein
- 背景
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Junctional Adhesion Molecule A (JAM-A) is a single-pass type I membrane protein that belongs to the immunoglobulin superfamily. JAM-A contains 2 Ig-like V-type (immunoglobulin-like) domains and Interacts with the ninth PDZ domain. JAM-A is localized to the tight junctions of both epithelial and endothelial cells. JAM-A seems to be involved in epithelial tight junction formation. JAM-A appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM-A, thereby preventing tight junction assembly. JAM-A plays a role in regulating monocyte transmigration involved in regulating integrity of the epithelial barrier. In the case of orthoreovirus infection, JAM-A serves as receptor for the virus.
Alternative Names: Junctional Adhesion Molecule A, JAM-A, Junctional Adhesion Molecule 1, JAM-1, Platelet F11 Receptor, Platelet Adhesion Molecule 1, PAM-1, CD321, F11R, JAM1, JCAM - 分子量
- 23.89 kDa
- UniProt
- Q9Y624
- 途径
- Cell-Cell Junction Organization
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