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F11R Protein (Fc Tag)

F11R 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7092719
发货至: 中国
  • 抗原 See all F11R 蛋白
    F11R (F11 Receptor (F11R))
    蛋白类型
    Recombinant
    宿主
    • 14
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    资源
    • 12
    • 5
    • 4
    • 3
    • 2
    HEK-293 Cells
    标记
    This F11R protein is labelled with Fc Tag.
    原理
    Recombinant Human JAM-A Protein with C-terminal human Fc tag
    特异性
    JAM-A (Ser28-Val238) hFc (Glu99-Ala330)
    产品特性
    Extracellular Domain Protein
    纯化方法
    affinity purification
    纯度
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product F11R 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with deionized water
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    F11R (F11 Receptor (F11R))
    别名
    JAM-A (F11R 产品)
    别名
    CD321 Protein, JAM Protein, JAM1 Protein, JAMA Protein, JCAM Protein, KAT Protein, PAM-1 Protein, 9130004G24 Protein, AA638916 Protein, ESTM33 Protein, JAM-1 Protein, JAM-A Protein, Jcam Protein, Jcam1 Protein, Ly106 Protein, Jam1 Protein, F11 receptor Protein, F11R Protein, F11r Protein
    背景
    Synonymes: CD321, JAM, JAM1, JAMA, JCAM, KAT, PAM-1
    Description: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.
    分子量
    predicted molecular mass of 49.1 kDa after removal of the signal peptide.The apparent molecular mass of JAM-A-hFc is 55-70 kDa due to glycosylation.
    UniProt
    Q9Y624
    途径
    Cell-Cell Junction Organization
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