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F11R Protein (Fc Tag)

F11R 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 94 % as determined by SDS-PAGE
产品编号 ABIN7320271
发货至: 中国
  • 抗原 See all F11R 蛋白
    F11R (F11 Receptor (F11R))
    蛋白类型
    Recombinant
    宿主
    • 15
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    小鼠
    资源
    • 12
    • 5
    • 4
    • 3
    • 2
    HEK-293 Cells
    标记
    This F11R protein is labelled with Fc Tag.
    原理
    Recombinant Mouse JAM-A/F11R Protein (Fc Tag)
    序列
    Met 1-Ala 242
    产品特性
    A DNA sequence encoding the mouse F11R (NP_766235.1) extracellular domain (Met 1-Ala 242) was fused with the Fc region of human IgG1 at the C-terminus.
    纯度
    > 94 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product F11R 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    F11R (F11 Receptor (F11R))
    别名
    JAM-A/F11R (F11R 产品)
    别名
    CD321 Protein, JAM Protein, JAM1 Protein, JAMA Protein, JCAM Protein, KAT Protein, PAM-1 Protein, 9130004G24 Protein, AA638916 Protein, ESTM33 Protein, JAM-1 Protein, JAM-A Protein, Jcam Protein, Jcam1 Protein, Ly106 Protein, Jam1 Protein, F11 receptor Protein, F11R Protein, F11r Protein
    背景

    Background: Junctional adhesion molecule-A (JAM-A), also known as F11 receptor (F11R) or Cluster of Differentiation 321 (CD321), is a transmembrane protein expressed at tight junctions of epithelial and endothelial cells, as well as on circulating leukocytes. JAM-A protein serves as a serotype-independent receptor for mammalian orthoreoviruses (reoviruses). It is also a ligand for the integrin LFA1, involves in leukocyte transmigration. As a cell adhesion molecule of the immunoglobulin superfamily, JAM-A protein involves in platelet adhesion, secretion and aggregation, and plays a crucial role in inflammatory thrombosis and atherosclerosis. In addition, it may be a potential therapeutic target for breast cancer.

    Synonym: 9130004G24,AA638916,ESTM33,JAM,JAM-1,JAM-A,Jcam,Jcam1,Ly106

    分子量
    50.2 kDa
    NCBI登录号
    NP_766235
    途径
    Cell-Cell Junction Organization
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