F11R Protein (AA 28-238) (His tag)
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- 抗原 See all F11R 蛋白
- F11R (F11 Receptor (F11R))
- 蛋白类型
- Recombinant
- 产品特性
- AA 28-238
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This F11R protein is labelled with His tag.
- 原理
- Human JAM-A Protein
- 序列
- Ser28-Val238.
- 产品特性
- Recombinant Human JAM-A Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser28-Val238.
- 纯度
- > 95 % as determined by Tris-Bis PAGE
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human JAM-A, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-JAM-A Antibody, hFc Tag with the EC50 of 8.8ng/ml determined by ELISA. See testing image for detail.
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F11 Receptor (F11R) (AA 27-238) protein (His tag)
F11R 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
F11 Receptor (F11R) (AA 26-238) protein (His tag)F11R 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
F11 Receptor (F11R) protein (His tag)F11R 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > (23.7+75.2) % as determined by SDS-PAGE
F11 Receptor (F11R) (AA 1-299) protein (GST tag)F11R 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
F11 Receptor (F11R) protein (Fc Tag)F11R 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 94 % as determined by SDS-PAGE
F11 Receptor (F11R) protein (Fc Tag)F11R 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 96 % as determined by SDS-PAGE
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- F11R (F11 Receptor (F11R))
- 别名
- JAM-A (F11R 产品)
- 别名
- CD321 Protein, JAM Protein, JAM1 Protein, JAMA Protein, JCAM Protein, KAT Protein, PAM-1 Protein, 9130004G24 Protein, AA638916 Protein, ESTM33 Protein, JAM-1 Protein, JAM-A Protein, Jcam Protein, Jcam1 Protein, Ly106 Protein, Jam1 Protein, F11 receptor Protein, F11R Protein, F11r Protein
- 背景
- Junctional adhesion molecule A (JAM-A), a cell adhesion molecule, is highly elevated in human GBM cancer stem cells and predicts poor patient prognosis. While JAM-A is also highly expressed in other cells in the tumor microenvironment, specifically microglia and macrophages,JAM-A functions to suppress pathogenic microglial activation in the female tumor microenvironment, highlighting an emerging role for sex differences in the GBM microenvironment and suggesting that sex differences extend beyond previously reported tumor cell-intrinsic differences.
- 分子量
- 24 kDa. Due to glycosylation, the protein migrates to 28-35 kDa based on Tris-Bis PAGE result.
- 途径
- Cell-Cell Junction Organization
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