Cathepsin B Protein (CTSB) (full length) (His tag)
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- 抗原 See all Cathepsin B (CTSB) 蛋白
- Cathepsin B (CTSB)
- 蛋白类型
- Recombinant
- 产品特性
- full length
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宿主
- 人
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资源
- 人细胞
- 标记
- This Cathepsin B protein is labelled with His tag.
- 原理
- Recombinant Human Cathepsin B/CTSB (C-6His)
- 序列
- RSRPSFHPVS DELVNYVNKR NTTWQAGHNF YNVDMGYLKR LCGTFLGGPK PPQRVMFTED LKLPASFDAR EQWPQCPTIK EIRDQGSCGS CWAFGAVEAI SDRICIHTNA HVSVEVSAED LLTCCGSMCG DGCNGGYPAE AWNFWTRKGL VSGGLYESHV GCRPYSIPPC EHHVNGSRPP CTGEGDTPKC SKICEPGYSP TYKQDKHYGY NSYSVSNSEK DIMAEIYKNG PVEGAFSVYS DFLLYKSGVY QHVTGEMMGG HAIRILGWGV ENGTPYWLVA NSWNTDWGDN GFFKILRGQD HCGIESEVVA GIPRTDQYWE KIVDHHHHHH
- 产品特性
- Recombinant Human Cathepsin B is produced by our mammalian expression system in human cells. The target protein is expressed with full length sequence of Human Cathepsin B fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product CTSB 蛋白
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Cathepsin B (CTSB) (AA 1-339) protein (GST tag)
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
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- 抗原
- Cathepsin B (CTSB)
- 别名
- cathepsin-b (CTSB 产品)
- 别名
- APPS Protein, CPSB Protein, CB Protein, apps Protein, cpsb Protein, LOC692390 Protein, CTSB Protein, cathepsin B Protein, cathepsin B S homeolog Protein, CTSB Protein, Ctsb Protein, ctsb.S Protein, LOC692390 Protein
- Sub Type
- Fusionprotein
- 背景
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Cathepsin B is an enzymatic protein belonging to the peptidase (or protease) families. The protein encoded by this gene is a lysosomal cysteine protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is a member of the peptidase C1 family. At least five transcript variants encoding the same protein have been found for this gene. Cystatin-B / CSTB is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B. Cystatin-B / CSTB is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Cystatin-B / CSTB is also thought to play a role in protecting against the proteases leaking from lysosomes
Alternative Names: Cathepsin B, APP Secretase, APPS, Cathepsin B1, CTSB, CPSB - 分子量
- 36.9 kDa
- UniProt
- P07858
- 途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
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