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Cathepsin B Protein (CTSB) (AA 18-339) (His tag)

This Recombinant Cathepsin B protein is expressed in HEK-293 Cells.
产品编号 ABIN7320464
发货至: 中国
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Quick Overview for Cathepsin B Protein (CTSB) (AA 18-339) (His tag) (ABIN7320464)

抗原

See all Cathepsin B (CTSB) 蛋白
Cathepsin B (CTSB)

蛋白类型

Recombinant

宿主

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小鼠

资源

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HEK-293 Cells

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 产品特性

    AA 18-339

    标记

    This Cathepsin B protein is labelled with His tag.

    原理

    Recombinant Mouse Cathepsin B/CTSB Protein (His Tag)

    序列

    His18-Phe339

    产品特性

    Recombinant Mouse Cathepsin B is produced by our Mammalian expression system and the target gene encoding His18-Phe339 is expressed with a 6His tag at the C-terminus.

    过滤

    0.2 μm filtered

    内毒素水平

    < 1.0 EU per μg of the protein as determined by the LAL method.

    Biological Activity Comment

    Not validated for activity
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    Cathepsin B (CTSB)

    别名

    Cathepsin B/CTSB

    背景

    Cathepsin B,Cathepsin B1,Ctsb,Cathepsin B (CatB) is an enzymatic protein belonging to the peptidase (or protease) families. It is the first described member of the family of lysosomal cysteine proteases. It is known to process a number of proteins, including pro and active caspases, prorenin and secretory leucoprotease inhibitor (SLPI). It is believed to participate in intracellular degradation and turnover of proteins. Cathepsin B may play a role in activation and inactivation of caspases, activation of renin and inactivation of SLPI, the key steps in apoptosis, angiotensin production, and progression of emphysema, respectively. Cathepsin B may also have a role in invasion and metastasis.

    分子量

    Calculated MW: 36.4 kDa

    Observed MW: 32-50 kDa

    UniProt

    P10605

    途径

    Activation of Innate immune Response, Toll-Like Receptors Cascades
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