PRKAA2 抗体
(Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| PRKAA2 抗体 (AA 453-552) | 人, 猴 | 小鼠 Monoclonal |
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| PRKAA2 抗体 (Center) | 人, 小鼠 | 兔 Polyclonal |
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| PRKAA2 抗体 (AA 453-552) | 人 | 小鼠 Monoclonal |
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| PRKAA2 抗体 (AA 351-450) | 人 | 兔 Polyclonal |
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| PRKAA2 抗体 (AA 1-552) | 人 | 小鼠 Polyclonal |
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| PRKAA2 抗体 (AA 265-294) | 人 | 兔 Polyclonal |
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| PRKAA2 抗体 (Thr172) | 人 | 兔 Polyclonal |
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| PRKAA2 抗体 (AA 343-552) | 人 | 兔 Polyclonal |
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| PRKAA2 抗体 (Catalytic Subunit) | 人 | 兔 Polyclonal |
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| PRKAA2 抗体 (AA 265-295) | 人, 小鼠 | 兔 Polyclonal |
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| PRKAA2 抗体 (Internal Region) | 人, 小鼠, 大鼠 | 山羊 Polyclonal |
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| PRKAA2 抗体 (C-Term) | 人 | 兔 Polyclonal |
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| Recombinant PRKAA2 抗体 (pThr172) | 人 | 兔 Monoclonal |
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| PRKAA2 抗体 (AA 252-493) | 人 | 兔 Polyclonal |
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| PRKAA2 抗体 (AA 1-552) | 人 | 兔 Polyclonal |
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| PRKAA2 抗体 (AA 350-400) | 人, 小鼠 | 兔 Polyclonal |
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| PRKAA2 抗体 (Internal Region) | 人, 小鼠, 大鼠, Cow, Pig, 犬 | 山羊 Polyclonal |
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| PRKAA2 抗体 (AA 323-372) | 人, 小鼠, 大鼠, Cow, Pig, 兔, 犬, 豚鼠, 猴, 马, 绵羊, 斑马鱼, Bat, 小鸡, 非洲爪蟾 | 兔 Polyclonal |
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| PRKAA2 抗体 (Internal Region) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| Recombinant PRKAA2 抗体 (pSer491) | 人 | 兔 Monoclonal |
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Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- 适用
- 人, 猴
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 8E11H5
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- AA 453-552
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- IP (Immunoprecipitation: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- ICC (Immunocytochemistry: 所列应用)
3 references - 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- Center
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- PLA (Proximity Ligation Assay: 有验证图片)
- RNAi (RNA Interference: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 1G8
- 标记
- unconjugated
- 抗体亚型
- IgG2a
- 抗原表位
- AA 453-552
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 有验证图片)
- WB (Western Blotting: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 351-450
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-552
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB15728
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 265-294
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB25835
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 145-173, Thr172
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 343-552
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 350-400, Catalytic Subunit
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB3173
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 265-295
Primary Antibody
- WB (Western Blotting: 有验证图片)
- EIA (Enzyme Immunoassay: 有验证图片)
- ELISA (ELISA: 所列应用)
- 质量等级
- Verified
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 山羊
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- Internal Region
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB11657
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 453-483, C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- 4F4
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
- 抗原表位
- pThr172
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 252-493
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-552
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 350-400
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠, Cow, Pig, 犬
- 宿主
- 山羊
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- Internal Region
Primary Antibody
- IF/ICC (Immunofluorescence (fixed cells): 有验证图片)
- WB (Western Blotting: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- Internal Region
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- 3H10
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
- 抗原表位
- pSer491
Latest Publications for our PRKAA2 抗体
: "Metformin protects against PM2.5-induced lung injury and cardiac dysfunction independent of AMP-activated protein kinase α2." in: Redox biology, Vol. 28, pp. 101345, (2020) (PubMed).
: "The evidence of metabolic-improving effect of metformin in Ay/a mice with genetically-induced melanocortin obesity and the contribution of hypothalamic mechanisms to this effect." in: PLoS ONE, Vol. 14, Issue 3, pp. e0213779, (2019) (PubMed).
: "Alternative polyadenylation drives genome-to-phenome information detours in the AMPKα1 and AMPKα2 knockout mice." in: Scientific reports, Vol. 8, Issue 1, pp. 6462, (2018) (PubMed).
: "Metformin ameliorates hepatic steatosis and improves the induction of autophagy in HFD‑induced obese mice." in: Molecular medicine reports, Vol. 16, Issue 1, pp. 680-686, (2017) (PubMed).
: "AMP-activated protein kinase stimulates Warburg-like glycolysis and activation of satellite cells during muscle regeneration." in: The Journal of biological chemistry, Vol. 290, Issue 44, pp. 26445-56, (2015) (PubMed).
: "High CO2 levels cause skeletal muscle atrophy via AMP-activated kinase (AMPK), FoxO3a protein, and muscle-specific Ring finger protein 1 (MuRF1)." in: The Journal of biological chemistry, Vol. 290, Issue 14, pp. 9183-94, (2015) (PubMed).
: "Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK." in: Nature, Vol. 482, Issue 7384, pp. 251-5, (2012) (PubMed).
: "Reduction of AMP-activated protein kinase alpha2 increases endoplasmic reticulum stress and atherosclerosis in vivo." in: Circulation, Vol. 121, Issue 6, pp. 792-803, (2010) (PubMed).
: "Alpha1-AMP-activated protein kinase regulates hypoxia-induced Na,K-ATPase endocytosis via direct phosphorylation of protein kinase C zeta." in: Molecular and cellular biology, Vol. 29, Issue 13, pp. 3455-64, (2009) (PubMed).
: "Stimulation of the AMP-activated protein kinase leads to activation of eukaryotic elongation factor 2 kinase and to its phosphorylation at a novel site, serine 398." in: The Journal of biological chemistry, Vol. 279, Issue 13, pp. 12220-31, (2004) (PubMed).
: "The evidence of metabolic-improving effect of metformin in Ay/a mice with genetically-induced melanocortin obesity and the contribution of hypothalamic mechanisms to this effect." in: PLoS ONE, Vol. 14, Issue 3, pp. e0213779, (2019) (PubMed).
: "Alternative polyadenylation drives genome-to-phenome information detours in the AMPKα1 and AMPKα2 knockout mice." in: Scientific reports, Vol. 8, Issue 1, pp. 6462, (2018) (PubMed).
: "Metformin ameliorates hepatic steatosis and improves the induction of autophagy in HFD‑induced obese mice." in: Molecular medicine reports, Vol. 16, Issue 1, pp. 680-686, (2017) (PubMed).
: "AMP-activated protein kinase stimulates Warburg-like glycolysis and activation of satellite cells during muscle regeneration." in: The Journal of biological chemistry, Vol. 290, Issue 44, pp. 26445-56, (2015) (PubMed).
: "High CO2 levels cause skeletal muscle atrophy via AMP-activated kinase (AMPK), FoxO3a protein, and muscle-specific Ring finger protein 1 (MuRF1)." in: The Journal of biological chemistry, Vol. 290, Issue 14, pp. 9183-94, (2015) (PubMed).
: "Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK." in: Nature, Vol. 482, Issue 7384, pp. 251-5, (2012) (PubMed).
: "Reduction of AMP-activated protein kinase alpha2 increases endoplasmic reticulum stress and atherosclerosis in vivo." in: Circulation, Vol. 121, Issue 6, pp. 792-803, (2010) (PubMed).
: "Alpha1-AMP-activated protein kinase regulates hypoxia-induced Na,K-ATPase endocytosis via direct phosphorylation of protein kinase C zeta." in: Molecular and cellular biology, Vol. 29, Issue 13, pp. 3455-64, (2009) (PubMed).
: "Stimulation of the AMP-activated protein kinase leads to activation of eukaryotic elongation factor 2 kinase and to its phosphorylation at a novel site, serine 398." in: The Journal of biological chemistry, Vol. 279, Issue 13, pp. 12220-31, (2004) (PubMed).
Aliases for PRKAA2 抗体
protein kinase AMP-activated catalytic subunit alpha 2 (PRKAA2) 抗体protein kinase AMP-activated catalytic subunit alpha 2 (Prkaa2) 抗体
protein kinase, AMP-activated, alpha 2 catalytic subunit (Prkaa2) 抗体
protein kinase, AMP-activated, alpha 2 catalytic subunit S homeolog (prkaa2.S) 抗体
protein kinase, AMP-activated, alpha 2 catalytic subunit (prkaa2) 抗体
2310008I11Rik 抗体
A830082D05 抗体
AMPK 抗体
Ampk 抗体
ampk 抗体
AMPK2 抗体
ampk2 抗体
AMPKa2 抗体
Ampka2 抗体
AMPKA2 抗体
AMPKalpha2 抗体
PRKAA 抗体
prkaa 抗体
prkaa1 抗体
PRKAA2 抗体
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