Premelanosome Protein 抗体
(Premelanosome Protein (PMEL))
This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| Melanoma gp100 抗体 | 人, 大鼠, 猴, 犬 | 小鼠 Monoclonal |
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| Melanoma gp100 抗体 (AA 376-502) | 人 | 小鼠 Monoclonal |
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| Melanoma gp100 抗体 | 人 | 小鼠 Monoclonal |
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| Melanoma gp100 抗体 (C-Term) | 人, 小鼠 | 兔 Polyclonal |
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| Melanoma gp100 抗体 (C-Term) | 人, 小鼠 | 山羊 Polyclonal |
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| Recombinant Melanoma gp100 抗体 | 人 | 兔 Monoclonal |
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| Melanoma gp100 抗体 | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| Melanoma gp100 抗体 (AA 25-467) | 人 | 兔 Polyclonal |
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| Recombinant Melanoma gp100 抗体 | 人 | 兔 Monoclonal |
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| Melanoma gp100 抗体 (N-Term) | 人, 马, 小鼠, 大鼠, 犬, Cow, 山羊, 豚鼠, 兔 | 兔 Polyclonal |
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| Melanoma gp100 抗体 | 人 | 兔 Polyclonal |
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| Melanoma gp100 抗体 (AA 25-300) | 人 | 兔 Polyclonal |
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| Melanoma gp100 抗体 (N-Term) | 人 | 兔 Polyclonal |
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| Melanoma gp100 抗体 (AA 1-661) | 人 | 兔 Polyclonal |
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| Recombinant Melanoma gp100 抗体 | 人 | Human Monoclonal |
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| Melanoma gp100 抗体 | 人, 马 | 小鼠 Monoclonal |
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| Melanoma gp100 抗体 (AA 412-440) | 人 | 兔 Polyclonal |
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| Recombinant Melanoma gp100 抗体 | 人 | Human, 兔 Chimeric |
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| Recombinant Melanoma gp100 抗体 | 人 | 兔 Monoclonal |
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| Melanoma gp100 抗体 (AA 1-661) | 人 | 小鼠 Polyclonal |
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Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 所列应用)
- IF (Immunofluorescence: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人, 大鼠, 猴, 犬
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 10E5
- 标记
- unconjugated
- 抗体亚型
- IgG2b
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 有验证图片)
- PAr (Protein Array: 有验证图片)
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- PMEL-2037
- 标记
- unconjugated
- 抗体亚型
- IgG1, kappa
- 抗原表位
- AA 376-502
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 有验证图片)
- SDS (SDS-PAGE: 有验证图片)
- FACS (Flow Cytometry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- HMB45
- 标记
- unconjugated
- 抗体亚型
- IgG1, kappa
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF/ICC (Immunofluorescence (fixed cells): 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- 质量等级
- Verified
- 适用
- 人, 小鼠
- 宿主
- 山羊
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 有验证图片)
- SDS (SDS-PAGE: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- PMEL-1825R
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG, kappa
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 25-467
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- 617R
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 有验证图片)
- IP (Immunoprecipitation: 所列应用)
1 reference - 适用
- 人, 马, 小鼠, 大鼠, 犬, Cow, 山羊, 豚鼠, 兔
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG, kappa
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 25-300
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IP (Immunoprecipitation: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-661
Primary Antibody
- SDS (SDS-PAGE: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- FACS (Flow Cytometry: 所列应用)
- ELISA (ELISA: 所列应用)
- BLI (Bio-Layer Interferometry: 所列应用)
- Func (Functional Studies: 所列应用)
- SPR (Surface Plasmon Resonance: 所列应用)
- 适用
- 人
- 宿主
- Human
- 克隆形成能力
- Monoclonal
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG1
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- FACS (Flow Cytometry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人, 马
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- SPM286
- 标记
- unconjugated
- 抗体亚型
- IgG2b, kappa
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB33755
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 412-440
Primary Antibody
- FACS (Flow Cytometry: 有验证图片)
- 适用
- 人
- 宿主
- Human, 兔
- 克隆形成能力
- Chimeric
- 克隆
- DMC420
- 标记
- unconjugated
- Fragment
- Fc fragment
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG1
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- PMEL-1825R
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-661
Latest Publications for our Premelanosome Protein 抗体
: "CXCL5 as Regulator of Neutrophil Function in Cutaneous Melanoma." in: The Journal of investigative dermatology, Vol. 139, Issue 1, pp. 186-194, (2019) (PubMed).
: "Reactive Neutrophil Responses Dependent on the Receptor Tyrosine Kinase c-MET Limit Cancer Immunotherapy. ..." in: Immunity, Vol. 47, Issue 4, pp. 789-802.e9, (2017) (PubMed).
: "A Preclinical Model of Malignant Peripheral Nerve Sheath Tumor-like Melanoma Is Characterized by Infiltrating Mast Cells." in: Cancer research, Vol. 76, Issue 2, pp. 251-63, (2016) (PubMed).
: "MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment." in: Nature communications, Vol. 6, pp. 8755, (2015) (PubMed).
: "Ultraviolet-radiation-induced inflammation promotes angiotropism and metastasis in melanoma. ..." in: Nature, Vol. 507, Issue 7490, pp. 109-13, (2014) (PubMed).
: "A lumenal domain-dependent pathway for sorting to intralumenal vesicles of multivesicular endosomes involved in organelle morphogenesis." in: Developmental cell, Vol. 10, Issue 3, pp. 343-54, (2006) (PubMed).
: "Functional amyloid formation within mammalian tissue." in: PLoS biology, Vol. 4, Issue 1, pp. e6, (2006) (PubMed).
: "Reactive Neutrophil Responses Dependent on the Receptor Tyrosine Kinase c-MET Limit Cancer Immunotherapy. ..." in: Immunity, Vol. 47, Issue 4, pp. 789-802.e9, (2017) (PubMed).
: "A Preclinical Model of Malignant Peripheral Nerve Sheath Tumor-like Melanoma Is Characterized by Infiltrating Mast Cells." in: Cancer research, Vol. 76, Issue 2, pp. 251-63, (2016) (PubMed).
: "MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment." in: Nature communications, Vol. 6, pp. 8755, (2015) (PubMed).
: "Ultraviolet-radiation-induced inflammation promotes angiotropism and metastasis in melanoma. ..." in: Nature, Vol. 507, Issue 7490, pp. 109-13, (2014) (PubMed).
: "A lumenal domain-dependent pathway for sorting to intralumenal vesicles of multivesicular endosomes involved in organelle morphogenesis." in: Developmental cell, Vol. 10, Issue 3, pp. 343-54, (2006) (PubMed).
: "Functional amyloid formation within mammalian tissue." in: PLoS biology, Vol. 4, Issue 1, pp. e6, (2006) (PubMed).
Aliases for Premelanosome Protein 抗体
premelanosome protein (PMEL) 抗体premelanosome protein (Pmel) 抗体
premelanosome protein b (pmelb) 抗体
premelanosome protein a (pmela) 抗体
cb397 抗体
D10H12S53E 抗体
D12S53E 抗体
D12S53Eh 抗体
fdv 抗体
gp87 抗体
gp100 抗体
ME20 抗体
ME20-M 抗体
ME20M 抗体
MMP115 抗体
P1 抗体
P100 抗体
PMEL17 抗体
Pmel17 抗体
pmel17 抗体
RPE1 抗体
sb:cb397 抗体
SI 抗体
Si 抗体
SIL 抗体
SILV 抗体
Silv 抗体
silva 抗体
silver 抗体
silverb 抗体
wu:fc11g11 抗体
wu:fj24g11 抗体
zgc:136622 抗体
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