PREX2 抗体
(DEP Domain Containing 2 (DEPDC2))
Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein- coupled receptors and phosphoinositide 3-kinase (By similarity).
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Aliases for PREX2 抗体
phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 (PREX2) 抗体phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 (Prex2) 抗体
6230420N16Rik 抗体
AI316880 抗体
AI553603 抗体
C030045D06Rik 抗体
D430013K02 抗体
DEP.2 抗体
DEPDC2 抗体
Depdc2 抗体
P-REX2 抗体
P-Rex2 抗体
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