PKC iota 抗体
(Protein Kinase C, iota (PRKCI))
This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| PKC iota 抗体 (AA 21-214) (Cy3) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| PKC iota 抗体 (AA 21-214) (Fluoro488) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| PKC iota 抗体 (AA 21-214) (Fluoro647) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| PKC iota 抗体 (AA 21-214) (PE) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| PKC iota 抗体 (N-Term) | 人 | 兔 Polyclonal |
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| PKC iota 抗体 | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| PKC iota 抗体 (AA 1-588) | 人 | 小鼠 Monoclonal |
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| PKC iota 抗体 (Center) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| PKC iota 抗体 (AA 100-300) | 人 | 小鼠 Monoclonal |
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| PKC iota 抗体 (AA 100-300) | 人 | 小鼠 Monoclonal |
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| PKC iota 抗体 (AA 100-300) | 人 | 小鼠 Monoclonal |
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| PKC iota 抗体 (AA 100-300) | 人 | 小鼠 Monoclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy3
- 抗体亚型
- IgG
- 抗原表位
- AA 21-214
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Fluoro488
- 抗体亚型
- IgG
- 抗原表位
- AA 21-214
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Fluoro647
- 抗体亚型
- IgG
- 抗原表位
- AA 21-214
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- PE
- 抗体亚型
- IgG
- 抗原表位
- AA 21-214
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 1G11
- 标记
- unconjugated
- 抗体亚型
- IgG1 kappa
- 抗原表位
- AA 1-588
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- Center
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- PRKCI-4912
- 标记
- unconjugated
- 抗体亚型
- IgG2b, kappa
- 抗原表位
- AA 100-300
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 质量等级
- Carrier-free
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- PRKCI-4912
- 标记
- unconjugated
- 抗体亚型
- IgG2b, kappa
- 抗原表位
- AA 100-300
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- PRKCI-4911
- 标记
- unconjugated
- 抗体亚型
- IgG2b, kappa
- 抗原表位
- AA 100-300
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 质量等级
- Carrier-free
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- PRKCI-4911
- 标记
- unconjugated
- 抗体亚型
- IgG2b, kappa
- 抗原表位
- AA 100-300
Latest Publications for our PKC iota 抗体
: "Actin-interacting protein 1 controls assembly and permeability of intestinal epithelial apical junctions." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 308, Issue 9, pp. G745-56, (2015) (PubMed).
: "Significance and expression of atypical protein kinase C-iota in human hepatocellular carcinoma." in: The Journal of surgical research, Vol. 154, Issue 1, pp. 143-9, (2009) (PubMed).
: "Correlation of aPKC-iota and E-cadherin expression with invasion and prognosis of cholangiocarcinoma." in: Hepatobiliary & pancreatic diseases international : HBPD INT, Vol. 7, Issue 1, pp. 70-5, (2008) (PubMed).
: "Protein kinase C (PKC) betaII induces cell invasion through a Ras/Mek-, PKC iota/Rac 1-dependent signaling pathway." in: The Journal of biological chemistry, Vol. 279, Issue 21, pp. 22118-23, (2004) (PubMed).
: "Rapid backbone 1H, 13C, and 15N assignment of the V1 domain of human PKC iota using the new program IBIS." in: Journal of biomolecular NMR, Vol. 26, Issue 4, pp. 373-4, (2003) (PubMed).
: "Rab2 interacts directly with atypical protein kinase C (aPKC) iota/lambda and inhibits aPKCiota/lambda-dependent glyceraldehyde-3-phosphate dehydrogenase phosphorylation." in: The Journal of biological chemistry, Vol. 278, Issue 52, pp. 52524-30, (2003) (PubMed).
: "Serotonin-induced MMP-13 production is mediated via phospholipase C, protein kinase C, and ERK1/2 in rat uterine smooth muscle cells." in: The Journal of biological chemistry, Vol. 277, Issue 45, pp. 42830-40, (2002) (PubMed).
: "NF-kappaB/RelA transactivation is required for atypical protein kinase C iota-mediated cell survival." in: Oncogene, Vol. 20, Issue 35, pp. 4777-92, (2001) (PubMed).
: "CD95 and TRAIL receptor-mediated activation of protein kinase C and NF-kappaB contributes to apoptosis resistance in ductal pancreatic adenocarcinoma cells." in: Oncogene, Vol. 20, Issue 31, pp. 4258-69, (2001) (PubMed).
: "Specific cellular proteins associate with angiotensin-converting enzyme and regulate its intracellular transport and cleavage-secretion." in: The Journal of biological chemistry, Vol. 275, Issue 30, pp. 23253-8, (2000) (PubMed).
: "Significance and expression of atypical protein kinase C-iota in human hepatocellular carcinoma." in: The Journal of surgical research, Vol. 154, Issue 1, pp. 143-9, (2009) (PubMed).
: "Correlation of aPKC-iota and E-cadherin expression with invasion and prognosis of cholangiocarcinoma." in: Hepatobiliary & pancreatic diseases international : HBPD INT, Vol. 7, Issue 1, pp. 70-5, (2008) (PubMed).
: "Protein kinase C (PKC) betaII induces cell invasion through a Ras/Mek-, PKC iota/Rac 1-dependent signaling pathway." in: The Journal of biological chemistry, Vol. 279, Issue 21, pp. 22118-23, (2004) (PubMed).
: "Rapid backbone 1H, 13C, and 15N assignment of the V1 domain of human PKC iota using the new program IBIS." in: Journal of biomolecular NMR, Vol. 26, Issue 4, pp. 373-4, (2003) (PubMed).
: "Rab2 interacts directly with atypical protein kinase C (aPKC) iota/lambda and inhibits aPKCiota/lambda-dependent glyceraldehyde-3-phosphate dehydrogenase phosphorylation." in: The Journal of biological chemistry, Vol. 278, Issue 52, pp. 52524-30, (2003) (PubMed).
: "Serotonin-induced MMP-13 production is mediated via phospholipase C, protein kinase C, and ERK1/2 in rat uterine smooth muscle cells." in: The Journal of biological chemistry, Vol. 277, Issue 45, pp. 42830-40, (2002) (PubMed).
: "NF-kappaB/RelA transactivation is required for atypical protein kinase C iota-mediated cell survival." in: Oncogene, Vol. 20, Issue 35, pp. 4777-92, (2001) (PubMed).
: "CD95 and TRAIL receptor-mediated activation of protein kinase C and NF-kappaB contributes to apoptosis resistance in ductal pancreatic adenocarcinoma cells." in: Oncogene, Vol. 20, Issue 31, pp. 4258-69, (2001) (PubMed).
: "Specific cellular proteins associate with angiotensin-converting enzyme and regulate its intracellular transport and cleavage-secretion." in: The Journal of biological chemistry, Vol. 275, Issue 30, pp. 23253-8, (2000) (PubMed).
Aliases for PKC iota 抗体
protein kinase C iota (PRKCI) 抗体protein kinase C, iota (prkci) 抗体
protein kinase C, iota (Prkci) 抗体
protein kinase C iota (Prkci) 抗体
2310021H13Rik 抗体
AI427505 抗体
aPKClambda 抗体
aPKC[l] 抗体
DXS1179E 抗体
hal 抗体
has 抗体
mKIAA4165 抗体
nPKC-iota 抗体
PKC 抗体
PKCI 抗体
Pkci 抗体
Pkcl 抗体
PKClambda 抗体
PRKCI 抗体
Prkcl 抗体
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