PKC iota 抗体 (AA 100-300)
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Quick Overview for PKC iota 抗体 (AA 100-300) (ABIN7869852)
抗原
See all PKC iota (PRKCI) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 100-300
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原理
- PKC iota Antibody / PRKCI (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A portion of amino acids 100-300 was used as the immunogen for the PKC iota antibody.
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亚型
- IgG2b, kappa
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应用备注
- Optimal dilution of the PKC iota antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the PKC iota antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- PKC iota (PRKCI) (Protein Kinase C, iota (PRKCI))
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别名
- PKC iota
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背景
- Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions, including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes, including conventional (c) PKC isoforms (, , , l/i, m and n). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of PKC i 1/2L and are independent of Ca2+. On the other hand, most of the other PKC members possess phorbol ester-binding activities and kinase activities.
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UniProt
- P41743
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途径
- Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, Tube Formation
抗原
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